Protein Alignment HOMER2 and homer1

DIOPT Version :10

• Sequence 1: XP_006720838.1
• Gene: HOMER2 / 9455
• HGNCID: 17513
• Length: 364
• Species: Homo sapiens
• Sequence 2: NP_001106603.1
• Gene: homer1 / 100127824
• XenbaseID: XB-GENE-5807410
• Length: 355
• Species: Xenopus tropicalis
• Alignment Length: 349
• Identity: 185/349 - (53%)
• Similarity: 254/349 - (72%)
• Gaps: 1/349 - (0%)

Human    13 EQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINSTITPNMTF 77
            |||||:||||||||||||||||:|.||.|||||||||.|||.|||||:||:|.||||||:|||||
 Frog     3 EQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINSTISPNMTF 67

Human    78 TKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQES- 141
            ||||||||||||||||||:|||||||..||||||||||.||||::||:|:|||:|.:|..||||
 Frog    68 TKTSQKFGQWADSRANTVYGLGFSSEHHLTKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQESA 132

Human   142 GRETPSSTQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQSAANVKKWEIELQTLRESNAR 206
            |.:..|.....|:||||||:.:.....|:..::|..:..:..|.|:|..|.||.||.||:.:||:
 Frog   133 GGDLQSPLTPESINGTDDERTTPDVTPNSEPRAEPTQNALPFTHSSAINKHWEAELATLKGNNAK 197

Human   207 LTTALQESAASVEQWKRQFSICRDENDRLRNKIDELEEQCSEINREKEKNTQLKRRIEELEAELR 271
            ||.||.||.|:|:|||:|.:..::|.:||..::.|||...::.|..:...|:|.::|:|||..|:
 Frog   198 LTAALLESTANVKQWKQQLAAYQEEAERLHKRVSELECLSNQANAVQSHKTELNQKIQELETTLK 262

Human   272 EKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHLKVEL 336
            :||.|::.|:::.|...:|..:.:.:|:||:..|..|:::|.::..|:..:|:|:..|...:..|
 Frog   263 KKEEEIERLKEEVEHAKELQDQKDSLSQKLQEVETHNKDMEGQLSDLEQRLEKSQNEQDAFRNNL 327

Human   337 KSFLEVLDGKIDDLHDFRRGLSKL 360
            |:.||:|||||.:|.:.|..|:||
 Frog   328 KTLLEILDGKIFELTELRDNLAKL 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOMER2	XP_006720838.1	EVH1_Homer_Vesl	13..121	CDD:269917	93/107 (87%)
		SMC_prok_B	<103..343	CDD:274008	96/240 (40%)
homer1	NP_001106603.1	EVH1_Homer_Vesl	3..111	CDD:269917	93/107 (87%)
		SMC_prok_B	<185..334	CDD:274008	53/148 (36%)