Protein Alignment HOMER3 and Homer3

DIOPT Version :10

• Sequence 1: NP_004829.3
• Gene: HOMER3 / 9454
• HGNCID: 17514
• Length: 361
• Species: Homo sapiens
• Sequence 2: XP_036009953.1
• Gene: Homer3 / 26558
• MGIID: 1347359
• Length: 368
• Species: Mus musculus
• Alignment Length: 313
• Identity: 266/313 - (84%)
• Similarity: 276/313 - (88%)
• Gaps: 9/313 - (2%)

Human    56 AKAIINSTVTPNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLTQFAEKFQEVKEAARLAREKS 120
            ::||||||||||||||||||||||||||||||||||||||||.||||||||||||||||||||||
Mouse    58 SQAIINSTVTPNMTFTKTSQKFGQWADSRANTVYGLGFASEQQLTQFAEKFQEVKEAARLAREKS 122

Human   121 QDGGELTSPALGLASHQVPPSPLVSANGPGEEKLFRSQSADAPGPTERERLKKMLSEGSVGEVQW 185
            |||||.||..|.|||||||||||||.|||||||||||||||.|||||||||||||||||||||||
Mouse   123 QDGGEFTSTGLALASHQVPPSPLVSTNGPGEEKLFRSQSADTPGPTERERLKKMLSEGSVGEVQW 187

Human   186 EAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEG 250
            |||||||||||.:||||||||||||.|||||||.||||||.|||||||||||.|.|....||||
Mouse   188 EAEFFALQDSNQRLAGALREANAAATQWRQQLEVQRAEAELLRQRVAELEAQVAVEPVRAGEKE- 251

Human   251 LGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQ-------DLETRNAELE 308
             ...||:|||||.||||||||||||:|:.|.|||.:.||||||||:||       ||||||||||
Mouse   252 -ATSQSVEQLEARVQTKDQEIQTLKNQSTGTREAPDTAEREETQQQVQVGCRTSADLETRNAELE 315

Human   309 HQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEAAP 361
            .|||:||.:||||||||||||||||||||||||.|||||||||||||||||||
Mouse   316 QQLRSMECNLEEARAERERARAEVGRAAQLLDVRLFELSELREGLARLAEAAP 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOMER3	NP_004829.3	Required for interaction with NFATC2. /evidence=ECO:0000269|PubMed:18218901	1..80		21/23 (91%)
		EVH1_Homer_Vesl	6..114	CDD:269917	54/57 (95%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..169		48/54 (89%)
		Smc	<166..>360	CDD:440809	162/200 (81%)
Homer3	XP_036009953.1	PH-like	<58..116	CDD:473070	54/57 (95%)
		antiphage_ZorA_2	<98..264	CDD:411476	143/167 (86%)
		Smc	<205..>367	CDD:440809	127/163 (78%)