Protein Alignment GGPS1 and BTS1

DIOPT Version :9

• Sequence 1: NP_001032354.1
• Gene: GGPS1 / 9453
• HGNCID: 4249
• Length: 300
• Species: Homo sapiens
• Sequence 2: NP_015256.1
• Gene: BTS1 / 856036
• SGDID: S000005990
• Length: 335
• Species: Saccharomyces cerevisiae
• Alignment Length: 316
• Identity: 128/316 - (40%)
• Similarity: 183/316 - (57%)
• Gaps: 30/316 - (9%)

Human     9 QRILLEPYKYLLQLPGKQVRTKLSQAFNHWLKVPEDKLQIIIEVTEMLHNASLLIDDIEDNSKLR 73
            :.::.:||.::|..|||..|..|....|..:.:|:|:|.|:.::.|:|||:||||||||||:.||
Yeast    20 ESLISKPYNHILLKPGKNFRLNLIVQINRVMNLPKDQLAIVSQIVELLHNSSLLIDDIEDNAPLR 84

Human    74 RGFPVAHSIYGIPSVINSANYVYFLGLEKV--LTLDHP---DAVKLFTRQLLELHQGQGLDIYWR 133
            ||...:|.|:|:||.||:|||:||..::.|  ||...|   :.:.:|..:|:.||:|||||||||
Yeast    85 RGQTTSHLIFGVPSTINTANYMYFRAMQLVSQLTTKEPLYHNLITIFNEELINLHRGQGLDIYWR 149

Human   134 D--NYTCPTEEEYKAMVLQKTGGLFGLAVGLMQLF---SDYKEDLKPLLNTLGLFFQIRDDYANL 193
            |  ....||:|.|..||:.||||||.|.:.||:..   |.:...|.|.:|.||:.:||||||.||
Yeast   150 DFLPEIIPTQEMYLNMVMNKTGGLFRLTLRLMEALSPSSHHGHSLVPFINLLGIIYQIRDDYLNL 214

Human   194 HSKEYSENKSFCEDLTEGKFSFPTIHAI------WSRPESTQVQNILRQRTENIDIKKYCVHYLE 252
            ...:.|..|.|.||:||||.|||.:||:      ....:..::..||..||.:.|||...:..||
Yeast   215 KDFQMSSEKGFAEDITEGKLSFPIVHALNFTKTKGQTEQHNEILRILLLRTSDKDIKLKLIQILE 279

Human   253 -DVGSFEYTRNTLKEL--------EAK-----AYKQIDARGGNPELVALVKHLSKM 294
             |..|..||:|.:.:|        |.|     |.....|...:.||:.::.|||::
Yeast   280 FDTNSLAYTKNFINQLVNMIKNDNENKYLPDLASHSDTATNLHDELLYIIDHLSEL 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GGPS1	NP_001032354.1	polyprenyl_synt	9..251	CDD:395277	111/257 (43%)
BTS1	NP_015256.1	polyprenyl_synt	20..278	CDD:395277	111/257 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C159051662
Domainoid	1	1.000	205	1.000	Domainoid score	I603
eggNOG	1	0.900	-	-		E1_COG0142
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31267
Inparanoid	1	1.050	220	1.000	Inparanoid score	I885
Isobase	1	0.950	-	0	Normalized mean entropy	S1150
OMA	1	1.010	-	-		QHG62161
OrthoFinder	1	1.000	-	-		FOG0007302
OrthoInspector	1	1.000	-	-		oto145666
orthoMCL	1	0.900	-	-		OOG6_103487
Panther	1	1.100	-	-	LDO	PTHR12001
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X7
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.710