Protein Alignment GGPS1 and qless

DIOPT Version :10

• Sequence 1: NP_004828.1
• Gene: GGPS1 / 9453
• HGNCID: 4249
• Length: 300
• Species: Homo sapiens
• Sequence 2: NP_733425.1
• Gene: qless / 43697
• FlyBaseID: FBgn0051005
• Length: 436
• Species: Drosophila melanogaster
• Alignment Length: 336
• Identity: 72/336 - (21%)
• Similarity: 136/336 - (40%)
• Gaps: 74/336 - (22%)

Human     8 VQRILLEPY--------------KYLLQL-----------------PGKQVRTK----LSQAFNH 37
            |:...::||              :|||:.                 .||.:|..    :::|.|:
  Fly   106 VREFQIDPYIILDDDLKYFYDDVRYLLKSGTSQPELDTIASYYFDGQGKALRPMVTMLMAKAINY 170

Human    38 WLKVPEDKL-----QIIIEVTEMLHNASLLIDDIEDNSKLRRGFPVAHSIYGIPSVINSANYVYF 97
            .|.....:|     ||.: .:||:|:|||:.||:.|.|..|||.|..::::....|..:.:|:..
  Fly   171 HLNNESHQLVHKQRQIAL-FSEMVHSASLVHDDVIDQSDFRRGKPSVNALWNHKKVTMAGDYILS 234

Human    98 LGLEKVLTLDHPDAVKLFTRQLLELHQGQGLDIYWRDNYTCPTEEE----YKAMVLQKTGGLFGL 158
            :....:..|...|...:.::.|.:|.||:.:.:..|:     ||.|    |.....:||..|...
  Fly   235 IASIMIARLRSDDVTIVLSQILTDLVQGEFMQLGSRE-----TENERFAHYLTKTYRKTASLIAN 294

Human   159 AVGLMQLFSDYKEDLKPLL----NTLGLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTIH 219
            |:....:.:...:::..:.    ..:||.||:.||..:..|......|....||..|..:.|.:.
  Fly   295 ALKATAVIAQADDNVAEVAFQYGRNIGLAFQLVDDMLDFVSSTEQMGKPTAADLKLGLATAPVLF 359

Human   220 AIWSRPESTQVQNILRQRTENIDIKKYCVHYLEDVGSFEYTRNT--LKELEAKAYKQIDARGGNP 282
            |....||...:  ::|:.:|..|:::          :||....:  |::....|.|..:
  Fly   360 ACEKYPELNPM--VMRRFSEPGDVER----------AFELVHKSHGLEQTRFLAKKHCN------ 406

Human   283 ELVALVKHLSK 293
            |.:.|.:.|::
  Fly   407 EAIRLAQELTE 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GGPS1	NP_004828.1	polyprenyl_synt	9..250	CDD:459773	63/288 (22%)
qless	NP_733425.1	polyprenyl_synt	138..387	CDD:459773	59/266 (22%)