Protein Alignment GGPS1 and fps1

DIOPT Version :9

• Sequence 1: NP_001032354.1
• Gene: GGPS1 / 9453
• HGNCID: 4249
• Length: 300
• Species: Homo sapiens
• Sequence 2: NP_593299.1
• Gene: fps1 / 2542898
• PomBaseID: SPAC6F12.13c
• Length: 347
• Species: Schizosaccharomyces pombe
• Alignment Length: 284
• Identity: 77/284 - (27%)
• Similarity: 127/284 - (44%)
• Gaps: 47/284 - (16%)

Human    45 KLQIIIEVTEMLHNASLLIDDIEDNSKLRRGFPVAHSIYGIPSV-INSA----NYVYFLGLEKVL 104
            |..::..:.|:|.:..|:.|||.|.||.|||.|..:.:.|:.:: ||.|    :.:||| |:|..
pombe    76 KAAVLGWMVELLQSFFLIADDIMDASKTRRGQPCWYLMPGVGNIAINDAFMVESAIYFL-LKKHF 139

Human   105 TLD--HPDAVKLFTRQLLELHQGQGLDIYWRDNYTCPTE---------EEYKAMVLQKTGGL-FG 157
            ..:  :.|.::||.....:...||.||:     .|.|.:         :::..:|:.||... |.
pombe   140 RQESCYVDLIELFHDVTFQTELGQQLDL-----LTAPEDSVDLSKFSLQKHSFIVIYKTAFYSFY 199

Human   158 LAVGLMQLFSDY--KEDLK---PLLNTLGLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPT 217
            |.|.|....:..  .|:||   .:|..||.:||::|||.:.:.......| ...|:.:.|.|: .
pombe   200 LPVALAMHLAGVATPENLKCAQDILIILGKYFQVQDDYLDCYGDPTVTGK-IGTDILDNKCSW-I 262

Human   218 IHAIWSR--PESTQV--QNILRQRTENIDIKKYCVHYLEDVGSFE-YTRNTLKELEAKAYKQIDA 277
            |:...::  ||...:  .|..|:.:|:....|.....|...|.|| |..:.:.|::    |.||
pombe   263 INLALAKCTPEQRVILDDNYGRKDSESEKRVKAVFEELNIRGEFENYEESEVSEIK----KLID- 322

Human   278 RGGNPELVALVK-----HLSKMFK 296
              |..|...|.|     .|.|::|
pombe   323 --GVDESTGLKKSIFTTFLGKIYK 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GGPS1	NP_001032354.1	polyprenyl_synt	9..251	CDD:395277	61/231 (26%)
fps1	NP_593299.1	polyprenyl_synt	44..304	CDD:278763	62/235 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0142
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810