Protein Alignment CD33 and Cd33

DIOPT Version :9

• Sequence 1: XP_011525833.1
• Gene: CD33 / 945
• HGNCID: 1659
• Length: 418
• Species: Homo sapiens
• Sequence 2: NP_001104528.1
• Gene: Cd33 / 12489
• MGIID: 99440
• Length: 403
• Species: Mus musculus
• Alignment Length: 302
• Identity: 162/302 - (53%)
• Similarity: 193/302 - (63%)
• Gaps: 23/302 - (7%)

Human    55 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGA 119
            :||.||.    ||:||.|..|.|...|||||:|||||.|||:.|:|...... .||.|.|.|:|.
Mouse     5 LPLFLLC----AGSLAQDLEFQLVAPESVTVEEGLCVHVPCSVFYPSIKLTL-GPVTGSWLRKGV 64

Human   120 IISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGS-TKYSY 183
            .:..||||||:...|.||:.|||||:|||||.:::|||.|.||::.|.|.||||:.|.. .:|||
Mouse    65 SLHEDSPVATSDPRQLVQKATQGRFQLLGDPQKHDCSLFIRDAQKNDTGMYFFRVVREPFVRYSY 129

Human   184 KSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHS 248
            |..|||:|||.|:..|.|:||||||.|:..||||||.|||||||||.|||:|.|.|||..|||.|
Mouse   130 KKSQLSLHVTSLSRTPDIIIPGTLEAGYPSNLTCSVPWACEQGTPPTFSWMSTALTSLSSRTTDS 194

Human   249 SVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVH 313
            |||..||:||||||.|||.|.|:|||||.|||||||||             ..||:...   :|.
Mouse   195 SVLTFTPQPQDHGTKLTCLVTFSGAGVTVERTIQLNVT-------------RKSGQMRE---LVL 243

Human   314 GAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHP 355
            .|:|.|.| .||.|.|||:|.||...|||..:.:|.....:|
Mouse   244 VAVGEATV-KLLILGLCLVFLIVMFCRRKTTKLSVHMGCENP 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CD33	XP_011525833.1	Ig	77..193	CDD:299845	62/116 (53%)
		IG_like	80..182	CDD:214653	53/102 (52%)
		ig	200..281	CDD:278476	58/80 (73%)
Cd33	NP_001104528.1	Ig	21..139	CDD:299845	63/118 (53%)
		IG_like	26..119	CDD:214653	51/93 (55%)
		Ig	150..214	CDD:299845	47/63 (75%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83965644
Domainoid	1	1.000	126	1.000	Domainoid score	I39015
eggNOG	1	0.900	-	-		E1_2CYFK
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	281	1.000	Inparanoid score	I15334
Isobase	0	0.000	Not matched by this tool.
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG33987
OrthoDB	1	1.010	-	-		D158400at40674
OrthoFinder	1	1.000	-	-		FOG0001383
OrthoInspector	1	1.000	-	-		oto126827
orthoMCL	1	0.900	-	-		OOG6_112647
Panther	1	1.100	-	-	O	PTHR12035
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X34
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	15.310