Protein Alignment GSTO1 and URE2

DIOPT Version :10

• Sequence 1: NP_004823.1
• Gene: GSTO1 / 9446
• HGNCID: 13312
• Length: 241
• Species: Homo sapiens
• Sequence 2: NP_014170.1
• Gene: URE2 / 855492
• SGDID: S000005173
• Length: 354
• Species: Saccharomyces cerevisiae
• Alignment Length: 247
• Identity: 56/247 - (22%)
• Similarity: 91/247 - (36%)
• Gaps: 61/247 - (24%)

Human    26 IYSMRFCPFAERTRLVLKAKGIRHEVI----NINLKNKPEWFFKKNPFGLVPVL-ENSQGQL-IY 84
            ::|.|..|...:..:||...|..:..|    |:.....|| |...||...||.| ::....| |:
Yeast   116 LFSHRSAPNGFKVAIVLSELGFHYNTIFLDFNLGEHRAPE-FVSVNPNARVPALIDHGMDNLSIW 179

Human    85 ES-AITCEYLDEAY--PGKKLLPDDPYEKACQKMI-----LELFSKVPSLVGS-----FIRSQN- 135
            || ||....:::.|  .|..||..|  :.|.|..|     .:.....| ::|.     :..||.
Yeast   180 ESGAILLHLVNKYYKETGNPLLWSD--DLADQSQINAWLFFQTSGHAP-MIGQALHFRYFHSQKI 241

Human   136 ---KEDYAGLKEEFRKEFTKLEEVLTNKK------------------TT------FFG------G 167
               .|.|.   :|.|:.:..:|..|..::                  ||      ||.      |
Yeast   242 ASAVERYT---DEVRRVYGVVEMALAERREALVMELDTENAAAYSAGTTPMSQSRFFDYPVWLVG 303

Human   168 NSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSE 219
            :.:::.|....||...::.:.:|..::. |::..|...|...|.|...|..|
Yeast   304 DKLTIADLAFVPWNNVVDRIGINIKIEF-PEVYKWTKHMMRRPAVIKALRGE 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GSTO1	NP_004823.1	GST_N_Omega	5..94	CDD:239353	22/74 (30%)
		GST_C_Omega	108..229	CDD:198293	29/156 (19%)
URE2	NP_014170.1	GST_N_Ure2p_like	114..194	CDD:239346	22/78 (28%)
		GST_C_Ure2p	208..350	CDD:198326	26/146 (18%)