Protein Alignment GSTO1 and GTT1

DIOPT Version :10

• Sequence 1: NP_004823.1
• Gene: GSTO1 / 9446
• HGNCID: 13312
• Length: 241
• Species: Homo sapiens
• Sequence 2: NP_012304.1
• Gene: GTT1 / 854856
• SGDID: S000001477
• Length: 234
• Species: Saccharomyces cerevisiae
• Alignment Length: 236
• Identity: 50/236 - (21%)
• Similarity: 95/236 - (40%)
• Gaps: 49/236 - (20%)

Human    23 SIRIYSMRFCPFAERTRL--VLKAKGIRHEVI----NINLKNKPEWFFKK-NPFGLVPVL----- 75
            |:.|..:.:...:...||  :|....:.:|::    :.|.:..||  .|| :|.|..|:|
Yeast     2 SLPIIKVHWLDHSRAFRLLWLLDHLNLEYEIVPYKRDANFRAPPE--LKKIHPLGRSPLLEVQDR 64

Human    76 ENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF----SKVPSLVGSFIRSQNK 136
            |..:.:::.||....:|:.:.:....:|..:..:.|.| :...||    |..|.|:..||.|:.|
Yeast    65 ETGKKKILAESGFIFQYVLQHFDHSHVLMSEDADIADQ-INYYLFYVEGSLQPPLMIEFILSKVK 128

Human   137 E-------DYAGLK-----------EEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLI-WPW-- 180
            :       .|...|           .|.:.:|..:|..: :|...:.....:|..|.|: :|.
Yeast   129 DSGMPFPISYLARKVADKISQAYSSGEVKNQFDFVEGEI-SKNNGYLVDGKLSGADILMSFPLQM 192

Human   181 -FERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEK 220
             |||..|     ..:..|.:..|:..:..:.:.:|  :.||
Yeast   193 AFERKFA-----APEDYPAISKWLKTITSEESYAA--SKEK 226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GSTO1	NP_004823.1	GST_N_Omega	5..94	CDD:239353	19/82 (23%)
		GST_C_Omega	108..229	CDD:198293	30/139 (22%)
GTT1	NP_012304.1	GST_N_GTT1_like	6..87	CDD:239344	17/82 (21%)
		GST_C_GTT1_like	93..218	CDD:198298	27/131 (21%)