Protein Alignment GSTO1 and YGR201C

DIOPT Version :10

• Sequence 1: NP_004823.1
• Gene: GSTO1 / 9446
• HGNCID: 13312
• Length: 241
• Species: Homo sapiens
• Sequence 2: NP_011717.4
• Gene: YGR201C / 853115
• SGDID: S000003433
• Length: 225
• Species: Saccharomyces cerevisiae
• Alignment Length: 227
• Identity: 36/227 - (15%)
• Similarity: 75/227 - (33%)
• Gaps: 92/227 - (40%)

Human    21 EGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNK-------PEWFFKKNPFGLVPVLENS 78
            |..:|.|.....|..|.|  :.:|..|.:.:|:::...:       ||..||            :
Yeast    47 EFPLRKYPTFVGPHDEWT--LTEAMAIDYYLIHLSSDKEAVRQLLGPEGDFK------------T 97

Human    79 QGQLI-YESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGL 142
            :..:: :||....::|:|                    :.|:|.   .|:|  ::..|..::...
Yeast    98 RADILRWESLSNSDFLNE--------------------VCEVFF---PLIG--VKPYNATEFKAA 137

Human   143 KEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMK 207
            :|.                           :|.::..:.:||:..:...|.||
Yeast   138 REN---------------------------VDTIVSLYEKRLKKQQYLVCDDH------------ 163

Human   208 EDPTVSALLTSEKDWQGFL----ELYLQNSPE 235
              .|::.|:::.....||:    |.:....||
Yeast   164 --ETLADLISAAAFSLGFISFFDETWRSKHPE 193

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GSTO1	NP_004823.1	GST_N_Omega	5..94	CDD:239353	15/80 (19%)
		GST_C_Omega	108..229	CDD:198293	17/124 (14%)
YGR201C	NP_011717.4	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	4..78	CDD:469754	9/32 (28%)
		GST_C_EF1Bgamma_like	98..220	CDD:198290	23/162 (14%)