Protein Alignment GSTO1 and GstO2

DIOPT Version :10

• Sequence 1: NP_004823.1
• Gene: GSTO1 / 9446
• HGNCID: 13312
• Length: 241
• Species: Homo sapiens
• Sequence 2: NP_729388.1
• Gene: GstO2 / 38974
• FlyBaseID: FBgn0035906
• Length: 251
• Species: Drosophila melanogaster
• Alignment Length: 212
• Identity: 78/212 - (36%)
• Similarity: 107/212 - (50%)
• Gaps: 12/212 - (5%)

Human    11 KGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVL 75
            :||..|....:|..|.:||.||||:.|.||:|.||.|.|..|.::|..||||:...:|.|.||.|
  Fly    10 RGSTKPELPEDGVPRFFSMAFCPFSHRVRLMLAAKHIEHHKIYVDLIEKPEWYKDFSPLGKVPAL 74

Human    76 E----NSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNK 136
            :    ..|..|: ||.|..||||:.||..:|.|.||.:||..|:::|.|:.|.|.:.. :.:.|.
  Fly    75 QLTGVKDQPTLV-ESLIIAEYLDQQYPQTRLFPTDPLQKALDKILIERFAPVVSAIYP-VLTCNP 137

Human   137 EDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNE------CVDH 195
            .........|.......|..|..:.|.:|.|..|.::||:|||||||..:||:|.      ....
  Fly   138 NAPKDAIPNFENALDVFEVELGKRGTPYFAGQHIGIVDYMIWPWFERFPSMKINTEQKYELDTKR 202

Human   196 TPKLKLWMAAMKEDPTV 212
            ..||..|...|.:|..|
  Fly   203 FEKLLKWRDLMTQDEVV 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GSTO1	NP_004823.1	GST_N_Omega	5..94	CDD:239353	37/86 (43%)
		GST_C_Omega	108..229	CDD:198293	33/111 (30%)
GstO2	NP_729388.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	5..96	CDD:469754	37/86 (43%)
		GST_C_Omega	110..235	CDD:198293	33/111 (30%)