DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CDY2A and Su(var)205

DIOPT Version :9

Sequence 1:	NP_004816.1	Gene:	CDY2A / 9426	HGNCID:	1810	Length:	541	Species:	Homo sapiens
Sequence 2:	NP_476755.1	Gene:	Su(var)205 / 34119	FlyBaseID:	FBgn0003607	Length:	206	Species:	Drosophila melanogaster

Alignment Length:	112	Identity:	33/112 - (29%)
Similarity:	61/112 - (54%)	Gaps:	7/112 - (6%)

- Green bases have known domain annotations that are detailed below.

Human     4 QEFEVEAIVDKRQDKNGNTQYLVRWKGYDKQDDTWEPEQHLMNCEKCVHDF--NRRQTEK---QK 63
            :|:.||.|:|:|..| |..:|.::||||.:.::|||||.:| :|:..:..:  :|:..||   .|
  Fly    22 EEYAVEKIIDRRVRK-GKVEYYLKWKGYPETENTWEPENNL-DCQDLIQQYEASRKDEEKSAASK 84

Human    64 KLTWTTTSRIFSNNARRRTSRSTKANYSKNSPKTPVTDKHHRSKNCK 110
            |...:::::......|..:|.||.:......|..|..:|..|:.:.:
  Fly    85 KDRPSSSAKAKETQGRASSSTSTASKRKSEEPTAPSGNKSKRTTDAE 131

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CDY2A	NP_004816.1	CHROMO	5..58	CDD:214605	21/54 (39%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	72..104		7/31 (23%)
		crotonase-like	287..483	CDD:119339
Su(var)205	NP_476755.1	CHROMO	24..72	CDD:237991	19/49 (39%)
Su(var)205	NP_476755.1	ChSh	141..202	CDD:197638
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910