DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Idh3b and CG32026

DIOPT Version :9

Sequence 1:	NP_446033.1	Gene:	Idh3b / 94173	RGDID:	621881	Length:	385	Species:	Rattus norvegicus
Sequence 2:	NP_729420.1	Gene:	CG32026 / 317829	FlyBaseID:	FBgn0052026	Length:	719	Species:	Drosophila melanogaster

Alignment Length:	340	Identity:	132/340 - (38%)
Similarity:	211/340 - (62%)	Gaps:	16/340 - (4%)

- Green bases have known domain annotations that are detailed below.

  Rat    51 VTMLPGDGVGPELMHAVKEVFKAAAVPVEFKEHHLSEVQNMASEEKL-EQVLSSMKENKVAIIGK 114
            :|::||||:|||:..||.::.:||..|:.|:...::.|.|......: |||:.||...||.:.|.
  Fly   385 ITLMPGDGIGPEISMAVIKILEAAKTPLIFEPVDVTPVLNSQGMTSVPEQVIESMNRTKVGLKGP 449

  Rat   115 IYTPMEYKGE-LASYDMQLRRKLDLFANVVHVKSLPGYKTRHNNLDLVIIREQTEGEYSSLEHES 178
            :.||:   |. ..|.::.||:..:|:||:...:||||.:|.:.::|:|.|||.||||||.:||..
  Fly   450 LMTPV---GTGFRSLNLTLRQLFNLYANIRPCRSLPGVETVYGDVDIVTIRENTEGEYSGIEHTL 511

  Rat   179 ARGVIECLKIVTRTKSQRIAKFAFDYATKKGRSKVTAVHKANIMKLGDGLFLQCCEEVAELYPK- 242
            ..||::.:|::||..|.|:|::.|.||....|.|||||.::.:|::.|||||:|..|:|..|..
  Fly   512 VNGVVQSIKLITRNASLRVAEYTFQYALAMKRKKVTAVAESQVMRMSDGLFLRCVREMAAKYKSK 576

  Rat   243 -----IKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAV 302
                 ||:|...:...|:.:||:|.::|:||:|||||:||.:..|||:||.|:.|..:.....|:
  Fly   577 MDQAGIKYEESTMTTVCLNIVQDPKRYDMLVLPNLYGDIISDTCAGLIGGLGLTPSGNVGTNGAI 641

  Rat   303 FET--GARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGG 365
            ||:  |.....|   |:::|||||:|||:..||.::.|..|:..|..||.|.|:...:||.|:||
  Fly   642 FESVHGTAPDIA---GKDLANPTALLLSSVMMLHYIGLHEHADKIEKAVLKTIRDDNIRTMDLGG 703

  Rat   366 YSTTTDFIKSVIGHL 380
            .:..:::..::|.:|
  Fly   704 KAKCSEYTDALIKNL 718

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idh3b	NP_446033.1	Iso_dh	47..380	CDD:294303	131/338 (39%)
CG32026	NP_729420.1	FGF-BP1	<281..361	CDD:284004
CG32026	NP_729420.1	Iso_dh	382..718	CDD:294303	131/338 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0473
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D325037at33208
OrthoFinder	1	1.000	-	-		FOG0000244
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820