Protein Alignment ORMDL3 and orm1

DIOPT Version :10

• Sequence 1: NP_644809.1
• Gene: ORMDL3 / 94103
• HGNCID: 16038
• Length: 153
• Species: Homo sapiens
• Sequence 2: NP_595290.1
• Gene: orm1 / 2540054
• PomBaseID: SPBC119.09C
• Length: 186
• Species: Schizosaccharomyces pombe
• Alignment Length: 145
• Identity: 63/145 - (43%)
• Similarity: 92/145 - (63%)
• Gaps: 1/145 - (0%)

Human     8 SEVNPNTRVMNSRGIWLSYVLAIGLLHIVLLSIPFVSVPVVWTLTNLIHNMGMYIFLHTVKGTPF 72
            |..|.|:..:|.:|.|:.:::.|..|.::..:||.||..:.||||||.:..|.:|..|.|.||||
pombe    30 SATNYNSNWVNYKGAWVIHIVLIAALRLIFHAIPSVSRELAWTLTNLTYMAGSFIMFHWVTGTPF 94

Human    73 ETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIVLYFLTSFYTKYDQIHFVLNTVSLMSVLIP 137
            |. :.|....||.|||:|.|.|:|.:||:|.:.||:|:.:::.||.|:...|::|..:|..||||
pombe    95 EF-NGGAYDRLTMWEQLDEGNQYTPARKYLLVLPIILFLMSTHYTHYNGWMFLVNIWALFMVLIP 158

Human   138 KLPQLHGVRIFGINK 152
            |||.:|..|||||.|
pombe   159 KLPAVHRKRIFGIQK 173

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ORMDL3	NP_644809.1	Important for ceramide level-sensing. /evidence=ECO:0000269|PubMed:37308477	1..17		3/8 (38%)
		ORMDL	11..146	CDD:461151	56/134 (42%)
orm1	NP_595290.1	COG5081	13..181	CDD:227413	63/145 (43%)