Protein Alignment ORMDL3 and ormdl1

DIOPT Version :10

• Sequence 1: NP_644809.1
• Gene: ORMDL3 / 94103
• HGNCID: 16038
• Length: 153
• Species: Homo sapiens
• Sequence 2: NP_001096387.1
• Gene: ormdl1 / 100124987
• XenbaseID: XB-GENE-948314
• Length: 153
• Species: Xenopus tropicalis
• Alignment Length: 153
• Identity: 130/153 - (84%)
• Similarity: 143/153 - (93%)
• Gaps: 0/153 - (0%)

Human     1 MNVGTAHSEVNPNTRVMNSRGIWLSYVLAIGLLHIVLLSIPFVSVPVVWTLTNLIHNMGMYIFLH 65
            ||||.||||||||||||||||:||:|.|.:|:||||||||||.||||.|||||:|||:|||:|||
 Frog     1 MNVGVAHSEVNPNTRVMNSRGMWLTYALGVGMLHIVLLSIPFFSVPVAWTLTNVIHNLGMYVFLH 65

Human    66 TVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIVLYFLTSFYTKYDQIHFVLNTVS 130
            .||||||||||||||||||||||:|||||||:|||||||:||:||||||||||||..||.:||.|
 Frog    66 AVKGTPFETPDQGKARLLTHWEQLDYGVQFTSSRKFLTISPIILYFLTSFYTKYDPTHFFINTAS 130

Human   131 LMSVLIPKLPQLHGVRIFGINKY 153
            |:|||||||||||||||||||||
 Frog   131 LLSVLIPKLPQLHGVRIFGINKY 153

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ORMDL3	NP_644809.1	Important for ceramide level-sensing. /evidence=ECO:0000269|PubMed:37308477	1..17		14/15 (93%)
		ORMDL	11..146	CDD:461151	112/134 (84%)
ormdl1	NP_001096387.1	ORMDL	11..146	CDD:461151	112/134 (84%)