DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CD80 and si:dkey-22i16.9

DIOPT Version :9

Sequence 1:	NP_005182.1	Gene:	CD80 / 941	HGNCID:	1700	Length:	288	Species:	Homo sapiens
Sequence 2:	XP_003197745.2	Gene:	si:dkey-22i16.9 / 100536567	ZFINID:	ZDB-GENE-090313-261	Length:	448	Species:	Danio rerio

Alignment Length:	200	Identity:	43/200 - (21%)
Similarity:	78/200 - (39%)	Gaps:	31/200 - (15%)

- Green bases have known domain annotations that are detailed below.

Human    28 LSHFCSGVIHVTKEVKEVATLSCGHNVSVEELAQT-RIYWQKEKKMVLTMMSGDMNIWPEYKNRT 91
            |..|....|:.|  |:..|.|.|......:...:| .|.|:|:.::||.:::|.:...|.:.:|.
Zfish   123 LEAFVPTTINTT--VRGKAKLPCYARTEKQISDETVNILWKKDDQVVLQVLNGIIKYGPRFTDRA 185

Human    92 IFDITN----NLSIVILALRPSDEGTYECVVLKYEKDAFKREHLAEVTLSVKA------------ 140
            ...:.:    .||:.|.....||.|.|:|    |.|.:.:..|...|||.|.|
Zfish   186 SVSLKDYKDGELSLTIHNASRSDAGLYQC----YHKPSEEHGHPGAVTLHVAALEISWTKKFGEN 246

Human   141 ---DFPTPSISDFEIPTSNIRRIICSTSGGFPEPHLSWLENGEELNAINTTVSQ---DPETELYA 199
               |..:..::...|.:....:.:|:..|...:....::.....:|  ||.|..   ..:..::.
Zfish   247 LPLDLFSSDVTISFIGSDESEKQVCTVMGNSTKCSSDYINRVSVIN--NTLVLSGLTSADKGIFT 309

Human   200 VSSKL 204
            |..|:
Zfish   310 VKDKI 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CD80	NP_005182.1	IgV_CD80	35..139	CDD:319335	29/108 (27%)
CD80	NP_005182.1	IgC_CD80	142..232	CDD:319332	9/65 (14%)
si:dkey-22i16.9	XP_003197745.2	IG_like	30..>110	CDD:214653
		IG_like	128..232	CDD:214653	29/109 (27%)
		Ig	137..214	CDD:299845	19/76 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1083437at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920