Protein Alignment SLC22A13 and CG7458

DIOPT Version :9

• Sequence 1: NP_004247.2
• Gene: SLC22A13 / 9390
• HGNCID: 8494
• Length: 551
• Species: Homo sapiens
• Sequence 2: NP_649374.1
• Gene: CG7458 / 40441
• FlyBaseID: FBgn0037144
• Length: 572
• Species: Drosophila melanogaster
• Alignment Length: 545
• Identity: 145/545 - (26%)
• Similarity: 247/545 - (45%)
• Gaps: 66/545 - (12%)

Human     7 VLAEIGDFGRFQIQLLILLCVLNFLSPFYFFAHVFMVLDEPHHCAV------------------- 52
            :|..||.|||:||...:||||....:.|:..::||......|.|.|
  Fly    41 ILVRIGQFGRYQIINYVLLCVPMLFNAFFSISYVFTASTVVHRCTVPQCDSPSSVYEEDWLGFTI 105

Human    53 -----AWVKNHTF--NLSAAEQLVLSVPLDTAGHPEPCLMFRPPPANASLQDILSHRFNET-QPC 109
                 ||...|.:  |:|.|          .:|:.:|           |.|..|...|..| :.|
  Fly   106 PKKNSAWDDCHRYAANISDA----------ISGYTDP-----------SGQYCLKEYFTITSETC 149

Human   110 DMGWEYPENRLPSLKNEFNLVCDRKHLKDTTQSVFMAGLLVGTLMFGPLCDRIGRKATILAQLLL 174
            ...:::.:.. .::..||.:.|:.:.......::...|..||..:.|...||.||:..:.....:
  Fly   150 GRDFKFRDEE-KTISTEFGIYCEDEWKLSMVGTINNVGQFVGIPLGGYFADRYGRRTMLAVAGSV 213

Human   175 FTLIGLATAFVPSFELYMALRFAVATAVAGLSFSNVTLLT-EWVGPSWRTQAVVLAQCNFSLGQM 238
            ..|:|:..:...::.:::...| :..||....|....||. |.|||..|..|..:....::||:.
  Fly   214 SALMGVIRSLSSNYSMFLVFEF-LDMAVGSTLFPTAFLLAIELVGPKRRVAAATIITIFYALGEA 277

Human   239 VLAGLAYGFRNWRLLQITGTAPGLLLFFYFWALPESARWLLTRGRMDEAIQLIQKAASVNRRKLS 303
            .|..||...::||.|.....||.:|...:.|.||||.||||::|..::|..::::||.:|:|.|.
  Fly   278 FLGFLASQVQHWRWLLRVLYAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAARINQRPLP 342

Human   304 PELMNQLVPEKTGPSGNALDLFRHPQLRKVTL----IIFC--VWFVDSLGYYGLSLQVGDFGLDV 362
            .|.:|.|:.........|.: .::|.:|.|..    |..|  .||..:|...||||...:.|.:.
  Fly   343 EEQLNDLLTSNRQKLSQANE-SQYPIMRAVVFFSLRIANCCLCWFTHTLIALGLSLNSVNLGGNK 406

Human   363 YLTQLIFGAVEVPARCSSIFMMQRFGRKWSQLGTLVLGGLMCIIII----FIPADLPVVVTMLAV 423
            |...::.|.:::|.....:.:|.|.||:.|...::    |:|.|.:    .:|||.......|.:
  Fly   407 YTNFMLNGFIQIPGLLLPLVIMDRVGRRHSLCASM----LLCAICMGASAAVPADNYAGSLALFL 467

Human   424 VGKMATAAAFTISYVYSAELFPTILRQTGMGLVGIFSRIGGILTPLVILLGEYHAALPMLIYGSL 488
            :||:|...:|.|.|.:::|:|||.:|.|.:.|..:..|||.:|.|...||.:|:...|.:::.:.
  Fly   468 IGKLAITCSFQILYFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLAKYYIYAPQILFATF 532

Human   489 PIVAGLLCTLLPETHGQGLKDTLQD 513
            .:::|.|....|||..:.|..|:::
  Fly   533 ALISGFLTLAFPETADKVLPTTIEE 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A13	NP_004247.2	2A0119	12..510	CDD:273328	142/535 (27%)
		MFS	139..500	CDD:119392	105/371 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	511..551		0/3 (0%)
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	142/535 (27%)
		MFS	161..544	CDD:119392	108/388 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	5.030