Protein Alignment SLC22A14 and CG7333

DIOPT Version :9

• Sequence 1: XP_006713479.2
• Gene: SLC22A14 / 9389
• HGNCID: 8495
• Length: 675
• Species: Homo sapiens
• Sequence 2: NP_650814.2
• Gene: CG7333 / 42334
• FlyBaseID: FBgn0038715
• Length: 541
• Species: Drosophila melanogaster
• Alignment Length: 565
• Identity: 128/565 - (22%)
• Similarity: 229/565 - (40%)
• Gaps: 101/565 - (17%)

Human   133 FANLLDAVGEFGTFQQRLVALTFIPSIMSAFFMFA--------DHFVFTAQKPYCNTSWILAVGP 189
            |:.:||..|.:|.||..::.|....:|:.:...|:        :|:.|.|.....:...|.:|..
  Fly     3 FSQVLDKCGNYGRFQVMILLLYGYTNILGSLHYFSQTLITFTPEHWCFHADLNGLSVEGIRSVYE 67

Human   190 HLSKAEQLNLTIPQAPNGSFLTCFMYLPVPWNLDSIIQFGLNDTDTCQDGWIY-PDAKKRSLINE 253
            ::|.:                :|...|.|      :...|:..|:.....||: .::...|:..|
  Fly    68 NISAS----------------SCTPLLGV------VNGTGVVSTNRKCRNWIFNRESGYESITTE 110

Human   254 FDLVCGMETKKDTAQIMFMAGLPIGSLIFRLITDKMGRYPAILLSLLGLIIFGFGTAFMNSFHLY 318
            ...||.........|..|..|..:|::||..::|::||.|::|::.|......|.|:|:::...:
  Fly   111 LKWVCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGRLPSLLMATLCGATGDFITSFVHTLPWF 175

Human   319 LFFRF--GISQSVVGYAISSISLATEWLVGEHRAHAI-ILGHCFFAVGAVLLTGIAYSLPHW-QL 379
            .|.||  |:|...:.|.:  ..|..|:|..:.|...: |:...|:..|.:.....|..:.:| :.
  Fly   176 AFSRFMSGLSTDTMYYLM--YILVFEYLSPKSRTFGLNIILAVFYCFGLMTSPWAAIWIGNWRRY 238

Human   380 LFLVG----GILVIPFISYIWILPESPRWLMMKGKVKEAKQVLCYAASVNKKTIPSNLLDELQLP 440
            |:|..    |:|:.||     ::.||.:||:.|.|..:|...|...|..|::.:..::.||.
  Fly   239 LWLASLPALGVLIYPF-----LICESAQWLLTKRKYDDAVICLKKVAKFNRRHVEESVFDEF--- 295

Human   441 RKKVTRASVLDFCKNRQLCKVTL-----VMSCVWFTVSYTYFTLSL----------------RMR 484
                     :.:.:.|:|....|     ....::.|.....|||:|                .|.
  Fly   296 ---------VKYYRERELQDYKLNSHEDTFLAMFLTPRLRRFTLTLLVKSVIITLSCDVINRNME 351

Human   485 ELGVSVHFRHVVPSIMEVPARLCCIFLLQQIGRKWSLAVTL----LQAIIWCLLLLFLPEGEDGL 545
            .||.|........||:.:||.:..:.|..:||||......|    |.......::..|...|:.|
  Fly   352 GLGTSPFKLFSFTSIVYLPAGVAILLLQNKIGRKGMACTALFVGGLITTATGFMIAHLDPTENAL 416

Human   546 RLKWPRCPATELKSMTILVLMLREFSLAATVTVFFLYTAELLPTVLRATGLGLVSLASVAGAILS 610
            .|              .:::.|..|....:......|.||::||.:|...:..:.:..:|.:.|:
  Fly   417 LL--------------AIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASSSLA 467

Human   611 LTII--SQTPSLLP-IFLCCVLAIVAFSLSSLLPETRDQPLSESL 652
            ..:|  :|....|| ||:.|::...| .|...||||.::.|.|:|
  Fly   468 FYVIYLAQYYKPLPSIFISCLMFFGA-GLCLTLPETLNKKLPETL 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A14	XP_006713479.2	2A0119	141..650	CDD:273328	123/553 (22%)
		MFS	270..641	CDD:119392	93/406 (23%)
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	123/554 (22%)
		MFS	126..499	CDD:119392	93/406 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153858
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.940