DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LIPG and CG6295

DIOPT Version :9

Sequence 1:	XP_005258447.1	Gene:	LIPG / 9388	HGNCID:	6623	Length:	536	Species:	Homo sapiens
Sequence 2:	NP_651521.1	Gene:	CG6295 / 43247	FlyBaseID:	FBgn0039471	Length:	338	Species:	Drosophila melanogaster

Alignment Length:	287	Identity:	88/287 - (30%)
Similarity:	136/287 - (47%)	Gaps:	49/287 - (17%)

- Green bases have known domain annotations that are detailed below.

Human   107 SQPLEDCSFNMTAKTFFIIHGWTMS-------GIFENWLHKLVSALHTREKDANVVVVDWLPLAH 164
            |..:....||....|.|.||||:.|       |:.:.|.         ...|.|::.|||.....
  Fly    84 SASISGSHFNPNHPTRFTIHGWSSSKDEFINYGVRDAWF---------THGDMNMIAVDWGRARS 139

Human   165 QLYTDAVNNTRVVGHSIARMLDWLQEKDDFSLGNVHLIGYSLGAHVAGYAGNFVK-GTVGRITGL 228
            ..|..:|.....||..:|.::::::.....:|.|..:||:||||||:||||..|| |.:..|.||
  Fly   140 VDYASSVLAVPGVGEQVATLINFMRSNHGLNLDNTMVIGHSLGAHVSGYAGKNVKNGQLHTIIGL 204

Human   229 DPAGPMFEGADIHKRLSPDDADFVDVLHTYTRSFGLSIGIQMPVGHIDIYPNGGDFQPGCGLNDV 293
            |||.|:|.....:||||..||.:|:.:.|.    |.::|...|:|....|||||..|||||: |:
  Fly   205 DPALPLFSYDSPNKRLSSTDAYYVESIQTN----GGTLGFLKPIGKGAFYPNGGKSQPGCGV-DL 264

Human   294 LGSIAYGTITEVVKCEHERAVHLFVDSLVNQDKPSFAFQCTDSNRFKKGICLSCRKNRCNSIGYN 358
            .||           |.|.|:|..:.:|:...:.|:  .:|.|   :::.:...|..:      |:
  Fly   265 TGS-----------CAHSRSVIYYAESVTENNFPT--MRCGD---YEEAVAKECGSS------YS 307

Human   359 AKKMRNKRNSKM-----YLKTRAGMPF 380
            :.:|....|:.|     |:..|:..|:
  Fly   308 SVRMGATTNAYMVAGDYYVPVRSDAPY 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LIPG	XP_005258447.1	Pancreat_lipase_like	85..376	CDD:238363	86/281 (31%)
		lipo_lipase	86..521	CDD:132274	88/287 (31%)
		PLAT_LPL	383..519	CDD:238856
CG6295	NP_651521.1	Pancreat_lipase_like	64..330	CDD:238363	86/281 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145238
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.940