Protein Alignment SLC22A8 and CG31103

DIOPT Version :9

• Sequence 1: NP_001171661.1
• Gene: SLC22A8 / 9376
• HGNCID: 10972
• Length: 542
• Species: Homo sapiens
• Sequence 2: NP_001097914.1
• Gene: CG31103 / 43030
• FlyBaseID: FBgn0051103
• Length: 506
• Species: Drosophila melanogaster
• Alignment Length: 490
• Identity: 106/490 - (21%)
• Similarity: 173/490 - (35%)
• Gaps: 144/490 - (29%)

Human    99 WVYNSTKDSI---VTEWDLVCNSNKL------KEMAQSIF----------------------MAG 132
            |.|:...:.|   .|:|.|:..|..|      .:.|.||.                      :.|
  Fly    15 WDYDMVLEKIGYGKTQWVLLLVSGLLTITSVAAQQAMSIIVIASQCEFETTQAEKGVMMAASVTG 79

Human   133 ILIGGLVLGDLSDRFGRRPIL-----------------TCSYL-----LLAASGSGAAFSPTFPI 175
            |.:...:.|.:||..|||.:|                 |..:|     ||.....||..:
  Fly    80 IFLSTYIWGYISDDIGRRRVLLYGNFASNALQFVLMFVTSVWLFNIINLLVGISVGAVSA----- 139

Human   176 YMVFRFLCGFGIS-----GITLSTVILNVE--WVPTRMRAIMSTALGYCYTFGQFILPGLAYAIP 233
             .::.:|..|.|.     .|..||:.::|.  :||.....::|:  .:..|.|.|:       ..
  Fly   140 -ALYAYLSEFNIPRHRAVAINYSTMFVSVTAIYVPATAWLVLSS--NWAITMGDFV-------FR 194

Human   234 QWRWLQLTVSIPFFVFFLSSWWTPESIRWLVLSGKSSKALKILRRVAVFNGKKEEGERLSLEELK 298
            .||.|.|...:|.|:..|...:.|||.::|:...|:::|::.:..::.||..|...:.||.:|..
  Fly   195 PWRLLLLVSLLPGFIGGLILLYYPESPKFLLSQEKNNEAIEAVAWISKFNRGKSIQQVLSCDEFT 259

Human   299 LNLQKEIS------------LAKAKYTASDLFRIPMLRRMTFC-LSL-----------AWF---- 335
            |..:..:.            |:|.......||..|.......| |:|           .||
  Fly   260 LKSEDPVGENLLGESQGCGILSKICRATIPLFHKPHGFNFILCNLALFGMFFSSNGMQLWFPEIV 324

Human   336 --ATGFAYYS------LAMGVEEFGV------------NLYILQIIFGGVDVPAKFITILSLSYL 380
              ::|....|      |::.||:..|            ..||..::.|...:....|..|.|:.|
  Fly   325 NRSSGAENNSSTVCEILSVPVEQPNVTETLDCTDPISSKTYIDNLVVGFAFLIGFSIQGLILNPL 389

Human   381 GRHTTQAAALLLAGGAILALTFVPLDLQTVRTVLAVFGKGCL-----SSSFSCLFLYTSELYPTV 440
            ||.....|||.:|..:.:.|.|    :::...||.:|   ||     ..|.|.:.....:|.||.
  Fly   390 GRKNVLLAALAVATLSGVLLHF----MESPTGVLVLF---CLYILLPGLSISIMIGAIVDLVPTH 447

Human   441 IRQTG---------MGVSNLWTRVGSMVSPLVKIT 466
            :|...         :|:......:|.|:.|....|
  Fly   448 LRSKAVSFCMSLGRLGIIAATNLMGVMLQPYCNTT 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A8	NP_001171661.1	2A0119	11..503	CDD:273328	106/490 (22%)
		MFS	96..493	CDD:119392	106/490 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	515..542
CG31103	NP_001097914.1	2A0115	29..475	CDD:273327	100/467 (21%)
		MFS	34..>189	CDD:119392	31/162 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153402
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840