DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment NHERF1 and Nherf1

DIOPT Version :10

Sequence 1:NP_004243.1 Gene:NHERF1 / 9368 HGNCID:11075 Length:358 Species:Homo sapiens
Sequence 2:NP_067605.1 Gene:Nherf1 / 59114 RGDID:708538 Length:356 Species:Rattus norvegicus


Alignment Length:359 Identity:314/359 - (87%)
Similarity:334/359 - (93%) Gaps:4/359 - (1%)


- Green bases have known domain annotations that are detailed below.


Human     1 MSADAAAGAPLPRLCCLEKGPNGYGFHLHGEKGKLGQYIRLVEPGSPAEKAGLLAGDRLVEVNGE 65
            ||||||||.|||||||||||||||||||||||||:||:||||||||||||:||||||||||||||
  Rat     1 MSADAAAGEPLPRLCCLEKGPNGYGFHLHGEKGKVGQFIRLVEPGSPAEKSGLLAGDRLVEVNGE 65

Human    66 NVEKETHQQVVSRIRAALNAVRLLVVDPETDEQLQKLGVQVREELLRAQEAPGQAEPPAAAEVQG 130
            ||||||||||||||||||||||||||||||||||:||||.:|||||||||.....||||||:.:.
  Rat    66 NVEKETHQQVVSRIRAALNAVRLLVVDPETDEQLKKLGVPIREELLRAQEKSEHTEPPAAADTKK 130

Human   131 AGNENEPREADKSHPEQRELRPRLCTMKKGPSGYGFNLHSDKSKPGQFIRSVDPDSPAEASGLRA 195
            ||::|   ||:|||.|:.|||||||||||||:||||||||||||||||||:||||||||||||||
  Rat   131 AGDQN---EAEKSHLERCELRPRLCTMKKGPNGYGFNLHSDKSKPGQFIRAVDPDSPAEASGLRA 192

Human   196 QDRIVEVNGVCMEGKQHGDVVSAIRAGGDETKLLVVDRETDEFFKKCRVIPSQEHLNGPLPVPFT 260
            ||||||||||||||||||||||||:|||||.||||||:|||||||||||.||||||:||||.||:
  Rat   193 QDRIVEVNGVCMEGKQHGDVVSAIKAGGDEAKLLVVDKETDEFFKKCRVTPSQEHLDGPLPEPFS 257

Human   261 NGEIQKENSREALAEAALESPRPALVRSASSDTSEELNSQDSPPKQDSTAPSST-SSSDPILDFN 324
            |||||||||||||.|.|.|||||||.||||||||||||:||||.:.|||.|||| ||||||||||
  Rat   258 NGEIQKENSREALVEPASESPRPALARSASSDTSEELNAQDSPKRHDSTEPSSTSSSSDPILDFN 322

Human   325 ISLAMAKERAHQKRSSKRAPQMDWSKKNELFSNL 358
            ||||:|||||||||||||||||||||||||||||
  Rat   323 ISLAVAKERAHQKRSSKRAPQMDWSKKNELFSNL 356

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NHERF1NP_004243.1 PDZ_NHERF-like 13..92 CDD:467249 75/78 (96%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 114..192 57/77 (74%)
PDZ_NHERF-like 153..232 CDD:467249 74/78 (95%)
EBP50_C 235..358 CDD:462654 108/123 (88%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 277..358 72/81 (89%)
Nherf1NP_067605.1 PDZ_NHERF-like 13..92 CDD:467249 75/78 (96%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 113..142 16/31 (52%)
PDZ_NHERF-like 150..229 CDD:467249 74/78 (95%)
EBP50_C 232..356 CDD:462654 108/123 (88%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 265..356 79/90 (88%)

Return to query results.
Submit another query.