Protein Alignment SLC9A3R1 and nrfl-1

DIOPT Version :9

• Sequence 1: NP_004243.1
• Gene: SLC9A3R1 / 9368
• HGNCID: 11075
• Length: 358
• Species: Homo sapiens
• Sequence 2: NP_741479.1
• Gene: nrfl-1 / 177736
• WormBaseID: WBGene00006438
• Length: 608
• Species: Caenorhabditis elegans
• Alignment Length: 380
• Identity: 94/380 - (24%)
• Similarity: 147/380 - (38%)
• Gaps: 84/380 - (22%)

Human    11 LPRLCCLEKG--PNGYGFHLHGEKGKLGQYIRLVEPGSPAEKAGLLAGDRLVEVNGENVEKET-H 72
            ||||..|.||  ...:||:||.|:|: |.:|..|:.|...|||||.||.|:|.|||:.:...| |
 Worm   281 LPRLAELNKGTPDQEFGFNLHAERGR-GHFIGTVDAGGIGEKAGLEAGQRIVGVNGQLIYPTTGH 344

Human    73 QQVVSRIRAALNAVRLLVVDPETD------------EQLQKLGVQV--------REELLRAQEAP 117
            ::||:.|:.......|||...:.|            :.::::..:.        ..|.:...::.
 Worm   345 KEVVALIKKDTMKTTLLVASEDVDKYHKDHNIAYSWDNVERVDTRPVINVETHHHHEEVSVPKSN 409

Human   118 GQAEPPA---AAEVQGAGNENEPREADKSHPEQRELRPRLCTMKKGPSGYGFNLHSDKSKPGQFI 179
            |...||.   :.:|      ||.||..|     .....|..|:....|.|.:     |.....:.
 Worm   410 GYDVPPLNPHSIQV------NEEREISK-----MTTTTRTETITNSNSAYQY-----KESSTAYD 458

Human   180 RSVDPDSPAEASGLRAQDRI---VEVNGVCMEGKQHGDVVSAIRAGGDETKLLVVDRETDEFFKK 241
            ....|  |.:::.|  .|.:   |.:.||.|  ..|.:|:.                .||:.
 Worm   459 AYATP--PVDSNDL--MDEVFGRVNLPGVTM--SSHTEVLP----------------PTDDI--- 498

Human   242 CRVIPSQEHLNGPLPVPFTNGEIQKENSREALAEAALESPRPALVRSASSDTSEELNSQDSPPKQ 306
            ..|.....|....:.||.         |.:.:...|.||.:.....|.:.....: :.|.||...
 Worm   499 SSVSSLSSHRESAVDVPV---------SHQYVPSYATESHQKHEQHSQTHHHHHQ-HQQPSPLSN 553

Human   307 DST---APSSTSSSDPILDFNISLAMAKERAHQKRSSKRAPQMDWSKKNELFSNL 358
            .|:   |.||||..|....:::|...|:||...|.......:|..::|.:|.||:
 Worm   554 GSSHGYAASSTSGYDDDDIYHLSAREARERLRMKNRKHHLHEMSLNEKYQLVSNM 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC9A3R1	NP_004243.1	PDZ_signaling	12..91	CDD:238492	35/81 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..192		16/80 (20%)
		PDZ_signaling	152..231	CDD:238492	15/81 (19%)
		EBP50_C	235..358	CDD:312529	30/125 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	277..358		23/83 (28%)
nrfl-1	NP_741479.1	PDZ_signaling	282..363	CDD:238492	35/81 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	53	1.000	Domainoid score	I8298
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	130	1.000	Inparanoid score	I3623
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D377274at33208
OrthoFinder	1	1.000	-	-		FOG0002256
OrthoInspector	1	1.000	-	-		otm15002
orthoMCL	1	0.900	-	-		OOG6_106590
Panther	1	1.100	-	-	LDO	PTHR14191
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5127
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.000