Protein Alignment RAB9A and Rab19

DIOPT Version :10

• Sequence 1: NP_004242.1
• Gene: RAB9A / 9367
• HGNCID: 9792
• Length: 201
• Species: Homo sapiens
• Sequence 2: NP_523970.1
• Gene: Rab19 / 38930
• FlyBaseID: FBgn0015793
• Length: 219
• Species: Drosophila melanogaster
• Alignment Length: 205
• Identity: 73/205 - (35%)
• Similarity: 111/205 - (54%)
• Gaps: 24/205 - (11%)

Human     7 LFKVILLGDGGVGKSSLMNRYVTNKFDTQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQERFRS 71
            |||::|:||.|.||:.:::|:.|..:..:..:||||:|..|.:.|:|..:.:||||||||||||:
  Fly    21 LFKIVLIGDCGTGKTCIVDRFKTGNYIERHGNTIGVDFSMKTIAVEGKQIKLQIWDTAGQERFRT 85

Human    72 LRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKIDISE-RQVST 135
            :...:||.::..|:.:.:....||.||..|.:|...|.    ..:...:::|||.|:.| |:|..
  Fly    86 ITQSYYRSANGVLIVYDITKRSSFSNLQKWIEEVRRYT----ASNVLIILVGNKCDLEEQREVDF 146

Human   136 EEAQAWCRDNGDYPY-FETSAKDATNVAAAFEEAVRRVLATEDRSDHLIQTDTVNLHRKP----- 194
            |||:..|:...:..: .|||||:..||..||     |.||.|.:..|    |..|:...|
  Fly   147 EEARQMCQYIPEILFVMETSAKENMNVEDAF-----RCLANELKRQH----DANNVEEVPENTIT 202

Human   195 ----KPSSSC 200
                ||..||
  Fly   203 LGQGKPLKSC 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB9A	NP_004242.1	Rab9	3..172	CDD:206697	61/166 (37%)
		Switch 1. /evidence=ECO:0000269|PubMed:34793709, ECO:0007744|PDB:7E1T	31..42		2/10 (20%)
		Switch 2. /evidence=ECO:0000269|PubMed:34793709, ECO:0007744|PDB:7E1T	64..78		7/13 (54%)
Rab19	NP_523970.1	Rab19	19..184	CDD:133267	64/171 (37%)