Protein Alignment RAB9A and RabX6

DIOPT Version :10

• Sequence 1: NP_004242.1
• Gene: RAB9A / 9367
• HGNCID: 9792
• Length: 201
• Species: Homo sapiens
• Sequence 2: NP_001261219.1
• Gene: RabX6 / 38084
• FlyBaseID: FBgn0035155
• Length: 222
• Species: Drosophila melanogaster
• Alignment Length: 213
• Identity: 68/213 - (31%)
• Similarity: 110/213 - (51%)
• Gaps: 32/213 - (15%)

Human     9 KVILLGDGGVGKSSLMNRYVTNKF--DTQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQERFRS 71
            ||||.||.|||||||..|:.||.|  ||....|:|::.::::..|:...:.:|:|||.|.||..|
  Fly    10 KVILCGDYGVGKSSLFRRFATNTFITDTDRKSTLGLDHIDREYSVNEKQIKLQLWDTGGMERVAS 74

Human    72 LRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKIDIS--ERQVS 134
            :.:.:|:.::..:|.|::|::.||.:||....:.:.||     |:....|.|||.|:.  |.:||
  Fly    75 VTSSYYKFAEGAILVFALDNAASFHSLSQHLLDIVTYA-----ENAKIFICGNKSDLDGREPEVS 134

Human   135 TEEAQAWCRD-----NGDYPYFETSAKDATNVAAAFEEAVRRVL----------ATEDRSDHLIQ 184
            .||.:|:|..     :..|   :||.:....|...|.:..|:::          |.|.:|   .|
  Fly   135 DEEVEAFCEQCHSLISATY---KTSCRSGAGVEEMFRDISRQLVHANRSKMELQALEHKS---FQ 193

Human   185 TDTVN--LHRKPKPSSSC 200
            .||.:  .....:.:|||
  Fly   194 VDTASSGAATNEEDASSC 211

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB9A	NP_004242.1	Rab9	3..172	CDD:206697	59/171 (35%)
		Switch 1. /evidence=ECO:0000269|PubMed:34793709, ECO:0007744|PDB:7E1T	31..42		4/12 (33%)
		Switch 2. /evidence=ECO:0000269|PubMed:34793709, ECO:0007744|PDB:7E1T	64..78		4/13 (31%)
RabX6	NP_001261219.1	Rab	10..172	CDD:206640	58/169 (34%)