Protein Alignment RAB9A and Rab4

DIOPT Version :10

• Sequence 1: NP_004242.1
• Gene: RAB9A / 9367
• HGNCID: 9792
• Length: 201
• Species: Homo sapiens
• Sequence 2: NP_523777.1
• Gene: Rab4 / 36992
• FlyBaseID: FBgn0016701
• Length: 213
• Species: Drosophila melanogaster
• Alignment Length: 169
• Identity: 66/169 - (39%)
• Similarity: 98/169 - (57%)
• Gaps: 6/169 - (3%)

Human     7 LFKVILLGDGGVGKSSLMNRYVTNKFDTQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQERFRS 71
            |||.:::|..|.|||.|::.::.:||.....|||||||.::.:.|.|..|.:|||||||||||||
  Fly     8 LFKFLIIGSAGSGKSCLLHHFIESKFKDDSSHTIGVEFGSRIVNVGGKSVKLQIWDTAGQERFRS 72

Human    72 LRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKIDISE-RQVST 135
            :...:|||:...||.:......||..|:||..:    |......:...:::|||.|:.| |.|:.
  Fly    73 VTRSYYRGAAGALLVYDATSRDSFNALTNWLND----ARTLASPNIVILLVGNKKDLEEARDVTF 133

Human   136 EEAQAWCRDNGDYPYFETSAKDATNVAAAFEEAVRRVLA 174
            .||..:.::| :..:.|||||...||..||.:..:.:||
  Fly   134 LEASTFAQEN-ELIFLETSAKTGENVEEAFLKCSKTILA 171

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB9A	NP_004242.1	Rab9	3..172	CDD:206697	64/165 (39%)
		Switch 1. /evidence=ECO:0000269|PubMed:34793709, ECO:0007744|PDB:7E1T	31..42		5/10 (50%)
		Switch 2. /evidence=ECO:0000269|PubMed:34793709, ECO:0007744|PDB:7E1T	64..78		8/13 (62%)
Rab4	NP_523777.1	Rab4	9..169	CDD:206696	63/164 (38%)