Protein Alignment RAB9A and Rab10

DIOPT Version :10

• Sequence 1: NP_004242.1
• Gene: RAB9A / 9367
• HGNCID: 9792
• Length: 201
• Species: Homo sapiens
• Sequence 2: NP_523419.1
• Gene: Rab10 / 33025
• FlyBaseID: FBgn0015789
• Length: 204
• Species: Drosophila melanogaster
• Alignment Length: 211
• Identity: 74/211 - (35%)
• Similarity: 120/211 - (56%)
• Gaps: 18/211 - (8%)

Human     1 MAGKS--SLFKVILLGDGGVGKSSLMNRYVTNKFDTQLFHTIGVEFLNKDLEVDGHFVTMQIWDT 63
            ||.|:  .|||::|:||.||||:.::.|:..:.|.:....|||::|..|.:|:.|..:.:|||||
  Fly     1 MAKKTYDLLFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDT 65

Human    64 AGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKIDI 128
            ||||||.::.|.:|||:...:|.:.:.:.:||:|:..|.:....:|:    |....:|||||.|:
  Fly    66 AGQERFHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHAN----EDVEKMILGNKCDM 126

Human   129 SE-RQVSTEEAQAWCRDNGDYPYFETSAKDATNVAAAFEEAVRRVL-------ATEDRSDHLIQT 185
            :: |.|:.|..:|..|::| ..:.|||||...|:..||.|....:|       :.|::...:|
  Fly   127 TDKRVVNKERGEAIAREHG-IRFMETSAKSNINIERAFCELAEAILDKTSGRESAENQERVII-- 188

Human   186 DTVNLHRKPKPSSSCC 201
            |..|..:.| ..|.||
  Fly   189 DRRNQEKAP-GYSKCC 203

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB9A	NP_004242.1	Rab9	3..172	CDD:206697	63/171 (37%)
		Switch 1. /evidence=ECO:0000269|PubMed:34793709, ECO:0007744|PDB:7E1T	31..42		3/10 (30%)
		Switch 2. /evidence=ECO:0000269|PubMed:34793709, ECO:0007744|PDB:7E1T	64..78		7/13 (54%)
Rab10	NP_523419.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	63/170 (37%)