Protein Alignment RAB9A and Rab9Fb

DIOPT Version :10

• Sequence 1: NP_004242.1
• Gene: RAB9A / 9367
• HGNCID: 9792
• Length: 201
• Species: Homo sapiens
• Sequence 2: NP_727472.1
• Gene: Rab9Fb / 32029
• FlyBaseID: FBgn0052670
• Length: 214
• Species: Drosophila melanogaster
• Alignment Length: 213
• Identity: 75/213 - (35%)
• Similarity: 115/213 - (53%)
• Gaps: 23/213 - (10%)

Human     7 LFKVILLGDGGVGKSSLMNRYVTNKFDTQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQERFRS 71
            |||:::|||.|||||.|:.|:..|:|..:...|:|::|..:::|:.|..|.:|||||||.|||:|
  Fly     7 LFKILVLGDIGVGKSCLLMRFSDNRFTEKHVCTVGMDFRVRNVELAGRMVMLQIWDTAGDERFKS 71

Human    72 LRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKI-DISERQVST 135
            |...:|||:...||.:.:..|:||:|:..|.||....:.    ||...:::|||. |:..|||..
  Fly    72 LLPSYYRGAHGILLVYDITSSKSFRNIDGWLKEIRRMSS----ESVNVMLVGNKCDDLDNRQVRM 132

Human   136 EEAQAWCRDNGDYPYFETSAKDATNVAAAFEEAV-----RRVLATEDRSDHLIQT-DT------- 187
            |:...:..... ..::|.|||...||...|....     |.|:.|.:|.....:| ||
  Fly   133 EQGFNYANHRA-LGFYEVSAKSGANVNDVFNMLSVGIYNRLVIHTPNRLSGGQETEDTAEPPDEP 196

Human   188 VNL----HRKPKPSSSCC 201
            :||    .::.|.|::||
  Fly   197 INLAGKDRQRAKDSNTCC 214

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB9A	NP_004242.1	Rab9	3..172	CDD:206697	63/170 (37%)
		Switch 1. /evidence=ECO:0000269|PubMed:34793709, ECO:0007744|PDB:7E1T	31..42		2/10 (20%)
		Switch 2. /evidence=ECO:0000269|PubMed:34793709, ECO:0007744|PDB:7E1T	64..78		7/13 (54%)
Rab9Fb	NP_727472.1	Rab	8..165	CDD:206640	61/161 (38%)