Protein Alignment KL and CG9701

DIOPT Version :10

• Sequence 1: NP_004786.2
• Gene: KL / 9365
• HGNCID: 6344
• Length: 1012
• Species: Homo sapiens
• Sequence 2: NP_648918.1
• Gene: CG9701 / 39872
• FlyBaseID: FBgn0036659
• Length: 541
• Species: Drosophila melanogaster
• Alignment Length: 506
• Identity: 182/506 - (35%)
• Similarity: 259/506 - (51%)
• Gaps: 74/506 - (14%)

Human    61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTH-HPLAPPGDSRNASLPLGAPSPLQPATGDV 124
            ||:.|||.|||::||.||||....||.||||..|| ||                ...:..:.|||
  Fly    26 FPNDFLWGVGSSSYQIEGGWNADDKGESIWDFLTHTHP----------------EKIVDRSNGDV 74

Human   125 ASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRELGVQPVV 189
            ::|||:...||.:.::||.|..||||:||.|::|.|.....:..|::||..|::.|....:.|:|
  Fly    75 SADSYHQWKRDVQMVKELHVGTYRFSLSWPRIMPGGYMNHVSTAGIKYYSNLIDELLRYNITPMV 139

Human   190 TLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLA 254
            |:|||:|||:||: .|||.|..:...|:|||.|....:|.:||.|.|::.|:.|..|||....:|
  Fly   140 TIYHWELPQKLQE-LGGWTNPEIIPLFKDYARLVLEMYGDRVKIWTTVNEPWHVCEHGYGVDYMA 203

Human   255 PGIR--GSPRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIALSSHWINPRRMTDHSIKEC- 316
            |...  |.|  .||..||||.|||:|.|:|...|:|.|||::.|.|.:.|..||.......:|.
  Fly   204 PSYNYPGIP--AYLCGHNLLKAHAEVVHMYRELFQPRQGGRMGITLDTSWPEPRDPNSAEDREAS 266

Human   317 QKSLDFVLGWFAKPVFI-DGDYPESM---KNNLS--------SILPDFTESEKKFIKGTADFFAL 369
            ::::.|.:|||..|:|. .|:||:.|   ..|||        |.||:||..|...|:||:|||.:
  Fly   267 ERAMQFYVGWFGHPIFSKHGNYPKVMIERIRNLSKEQGFGARSRLPEFTTEEIHRIRGTSDFFGI 331

Human   370 CFGPTLSFQLLDPHMKFRQLESPN------------------------------LRQLLSWIDLE 404
             ...|.:....:.|....:...|:                              :..||.||..|
  Fly   332 -NSYTSNLVTSNGHNNTGKFPVPSFNHDMGVVESQEGVDWPGSGSVWLKVYPKGMYNLLMWIHRE 395

Human   405 FNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVDVIGYTAWSLMDGFEWHRG 469
            :|.|:|.:.|||  ||.....:|...:.|...::...|.|:: ||.::.||.||||||.:||..|
  Fly   396 YNAPEIIVTENG--VSDRGGLEDYARVDYYNLYLSAVLDAME-DGANISGYIAWSLMDSYEWKAG 457

Human   470 YSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIEKNGF-----PPLPENQPL 515
            :|.:.||::|||.|..:...||.||..:.:|.:.|..     |.|.|.|.|
  Fly   458 FSEKFGLYHVDFNSPQRTRTPKISARVFAQLCKTNTIDWSYRPKLDEEQQL 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KL	NP_004786.2	Glycosyl hydrolase-1 1	57..506		177/490 (36%)
		Glycosyl hydrolases	58..506	CDD:474034	177/490 (36%)
		Glycosyl hydrolase-1 2	515..953		1/1 (100%)
		Glycosyl hydrolases	517..953	CDD:474034
CG9701	NP_648918.1	Glycosyl hydrolases	22..492	CDD:474034	176/488 (36%)