Protein Alignment SLC22A6 and CG31103

DIOPT Version :9

• Sequence 1: NP_004781.2
• Gene: SLC22A6 / 9356
• HGNCID: 10970
• Length: 563
• Species: Homo sapiens
• Sequence 2: NP_001097914.1
• Gene: CG31103 / 43030
• FlyBaseID: FBgn0051103
• Length: 506
• Species: Drosophila melanogaster
• Alignment Length: 450
• Identity: 85/450 - (18%)
• Similarity: 170/450 - (37%)
• Gaps: 111/450 - (24%)

Human   142 MVGVLLGAMVFGYLADRLGRRKVLIL-NYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGIS-- 203
            :.|:.|...::||::|.:|||:||:. |:...|:. ....|..:..::....||.|:::..:|
  Fly    77 VTGIFLSTYIWGYISDDIGRRRVLLYGNFASNALQ-FVLMFVTSVWLFNIINLLVGISVGAVSAA 140

Human   204 -----------------LNCMTLNVEWMPIHTRACVGTLI--GYVYSLGQFLLAGVAYAVPHWRH 249
                             :|..|:.|....|:..|....::  .:..::|.|:..       .||.
  Fly   141 LYAYLSEFNIPRHRAVAINYSTMFVSVTAIYVPATAWLVLSSNWAITMGDFVFR-------PWRL 198

Human   250 LQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQ 314
            |.|:...|.|...:...::.||.::..|..:.:..:.|:..:::.|..:.....||.:  ..:|:
  Fly   199 LLLVSLLPGFIGGLILLYYPESPKFLLSQEKNNEAIEAVAWISKFNRGKSIQQVLSCD--EFTLK 261

Human   315 KELTMGK---GQASAMELLR--CPTLRHLF---------LCLSMLWFATSFAYYGLVMDLQGFGV 365
            .|..:|:   |::....:|.  |.....||         ||        :.|.:|:.....|..:
  Fly   262 SEDPVGENLLGESQGCGILSKICRATIPLFHKPHGFNFILC--------NLALFGMFFSSNGMQL 318

Human   366 ---------------SIYLIQVIFGAVDLP-------------------------AKLVGF---- 386
                           |..:.:::...|:.|                         |.|:||
  Fly   319 WFPEIVNRSSGAENNSSTVCEILSVPVEQPNVTETLDCTDPISSKTYIDNLVVGFAFLIGFSIQG 383

Human   387 LVINSLGRRPAQMAALLLAGICILLNGVIPQDQSIVRTSLAVLGKGCL-----AASFNCIFLYTG 446
            |::|.|||:...:|||.:|    .|:||:   ...:.:...||...||     ..|.:.:.....
  Fly   384 LILNPLGRKNVLLAALAVA----TLSGVL---LHFMESPTGVLVLFCLYILLPGLSISIMIGAIV 441

Human   447 ELYPTMIRQTGMGMGSTMARVGSIVSP-LVSMTAELYPSMPLFIYGAVPVAASAVTVLLP 505
            :|.||.:|...:....::.|:|.|.:. |:.:..:.|.:....::....:....:...||
  Fly   442 DLVPTHLRSKAVSFCMSLGRLGIIAATNLMGVMLQPYCNTTFAMFTCTLIVCIVIVHYLP 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A6	NP_004781.2	2A0119	11..515	CDD:273328	84/449 (19%)
		MFS	135..505	CDD:119392	83/448 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	525..563
CG31103	NP_001097914.1	2A0115	29..475	CDD:273327	82/422 (19%)
		MFS	34..>189	CDD:119392	22/112 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153408
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840