DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ZFAND4 and rhp23

DIOPT Version :9

Sequence 1:	XP_016872420.1	Gene:	ZFAND4 / 93550	HGNCID:	23504	Length:	741	Species:	Homo sapiens
Sequence 2:	NP_596231.1	Gene:	rhp23 / 2540481	PomBaseID:	SPBC2D10.12	Length:	368	Species:	Schizosaccharomyces pombe

Alignment Length:	259	Identity:	51/259 - (19%)
Similarity:	85/259 - (32%)	Gaps:	78/259 - (30%)

- Green bases have known domain annotations that are detailed below.

Human   254 PKKAVKIKPHPPVAPRPSSGSTAPSRHRLLRVLPNIGQSCSPAFGNAYPPEISRNGISSLATQLS 318
            ||.|....|:|| |..|.....|||        ..:.:|.|..      ..::....|:..|..:
pombe    82 PKSAASPAPNPP-ASVPEKKVEAPS--------STVAESTSTT------QTVAAAAPSNPDTTAT 131

Human   319 AERYISSITGEFLKEDNSWENNTLS-HFSSNVKLPPQIPHLELGNDQELADSVLHLGSSLP-RQT 381
            :|..|.:              |||: ....||.:...:   |:|.::...:..:....:.| |..
pombe   132 SEAPIDA--------------NTLAVGAQRNVAVENMV---EMGYERSEVERAMRAAFNNPDRAV 179

Human   382 KHFLGNLPSSNGN-------IVLPSEECVTEQSLLP-------KVGSLASFAEGNADEQSSGLEG 432
            ::.|..:|....|       ..|.:::..:| :|.|       .:...|:.:|....||.|...|
pombe   180 EYLLTGIPEDILNRQREESAAALAAQQQQSE-ALAPTSTGQPANLFEQAALSENENQEQPSNTVG 243

Human   433 ACKVN---------------------LELLLTNADKGLKA--------PEQHLKHVAGVLNGES 467
            ...:.                     ||.:|....:|..|        ||..|:.:|....|||
pombe   244 DDPLGFLRSIPQFQQLRQIVQQNPQMLETILQQIGQGDPALAQAITQNPEAFLQLLAEGAEGES 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZFAND4	XP_016872420.1	None
rhp23	NP_596231.1	rad23	1..363	CDD:273167	51/259 (20%)
		RAD23_N	1..76	CDD:176400
		UBA1_Rhp23p_like	141..187	CDD:270561	8/48 (17%)
		XPC-binding	247..302	CDD:286376	9/54 (17%)
		UBA2_Rhp23p_like	321..360	CDD:270564
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900