Protein Alignment LHX2 and Awh

DIOPT Version :9

• Sequence 1: NP_004780.3
• Gene: LHX2 / 9355
• HGNCID: 6594
• Length: 406
• Species: Homo sapiens
• Sequence 2: NP_001261379.1
• Gene: Awh / 38451
• FlyBaseID: FBgn0013751
• Length: 287
• Species: Drosophila melanogaster
• Alignment Length: 356
• Identity: 105/356 - (29%)
• Similarity: 161/356 - (45%)
• Gaps: 92/356 - (25%)

Human    53 CAGCGGKISDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRFSVQRCAR 117
            ||.||..||||::|......||..||:||.|...|:.:.:||.::..:|||.||.:.|.. :|::
  Fly     8 CAACGEPISDRFFLEVGGCSWHAHCLRCCMCMCPLDRQQSCFIRERQVYCKADYSKNFGA-KCSK 71

Human   118 CHLGISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHFEALLQGEYPAHFN 182
            |..|||||:.|.|||:||:||.||.|..|.:.|:||:.|.:.|..|.|:.|:...::|
  Fly    72 CCRGISASDWVRRARELVFHLACFACDQCGRQLSTGEQFALMDDRVLCKAHYLETVEG------- 129

Human   183 HADVAAAAAAAAAAKSAGLGAAGANPLGLPYYNGVGTVQKGRPRKRKSPGPGADLAAYNAALSCN 247
                                               ||.         |...|.|
  Fly   130 -----------------------------------GTT---------SSDEGCD----------- 139

Human   248 ENDAEHLDRDQPYPSSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQV 312
             .|..|         ..||||:||:|...||:.:::.|.|:.|||.:||:::|..|||:|||.||
  Fly   140 -GDGYH---------KSKTKRVRTTFTEEQLQVLQANFQIDSNPDGQDLERIASVTGLSKRVTQV 194

Human   313 WFQNARAKFRRNLLRQENTGVDKSTDAALQTGTPSGPA------SELSNASLSPSSTPTTLTDLT 371
            ||||:||:.::::    :.|.:|..:       |.|.:      .:|:.:..:.:..|..|....
  Fly   195 WFQNSRARQKKHI----HAGKNKIRE-------PEGSSFARHINLQLTYSFQNNAQNPMHLNGSK 248

Human   372 SPTLPTVTSVLTSVPGNLEGHEPHSPSQTTL 402
            :...||..|.:..:..:...|  ..||:. |
  Fly   249 AGLYPTHESSMDELSQDSSVH--CMPSEVXL 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LHX2	NP_004780.3	LIM1_Lhx2	43..106	CDD:188853	22/52 (42%)
		LIM2_Lhx2_Lhx9	111..169	CDD:188763	26/57 (46%)
		COG5576	<247..378	CDD:227863	41/136 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	250..270		6/19 (32%)
		Homeobox	270..323	CDD:395001	27/52 (52%)
		Nuclear localization signal. /evidence=ECO:0000255	307..323		11/15 (73%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	328..374		7/51 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	387..406		4/16 (25%)
Awh	NP_001261379.1	LIM1_AWH	8..61	CDD:188759	22/52 (42%)
		LIM2_AWH	69..123	CDD:188765	26/53 (49%)
		Homeobox	152..204	CDD:278475	27/51 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910