DRSC/TRiP Functional Genomics Resources

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Protein Alignment LHX2 and Vsx1

DIOPT Version :9

Sequence 1:NP_004780.3 Gene:LHX2 / 9355 HGNCID:6594 Length:406 Species:Homo sapiens
Sequence 2:NP_001284898.1 Gene:Vsx1 / 31470 FlyBaseID:FBgn0263511 Length:837 Species:Drosophila melanogaster


Alignment Length:298 Identity:79/298 - (26%)
Similarity:105/298 - (35%) Gaps:108/298 - (36%)


- Green bases have known domain annotations that are detailed below.


Human   168 HFEALLQGEYPAHFNHADV-----------AAAAAAAAAAKS----AGLGA---AGANPLGLPYY 214
            |..|.....:.||..||..           ||.||.||.|.:    |.|||   ||.||..|...
  Fly   309 HHAAAAAAAHHAHHAHAQAHAHAHAHVHAHAAHAAHAAHAHAHHAEAFLGAAGGAGGNPNSLLAA 373

Human   215 NGVGTVQKGRPRKRKSPGPGADLAAYNAALSCNENDAEHLDRDQPYPSSQKTKRM--RTSFKHHQ 277
            :| |.|..|    ....|||                           ..:|.||.  ||.|...|
  Fly   374 HG-GDVLVG----PGGTGPG---------------------------GKKKNKRRHGRTIFTSSQ 406

Human   278 LRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRN------------------ 324
            |..::..|...|.||....:.|:.||||.:..:|||:||.|||:|:.                  
  Fly   407 LEELEKAFKEAHYPDVSARELLSMKTGLAEDRIQVWYQNRRAKWRKTEKCWGHSTKMAEYGLYGA 471

Human   325 LLR-------------QENTGV--------DKSTDAA-LQTGTPSG---PASELSNASLSPSSTP 364
            ::|             :|:..|        .||.:|| |.....|.   |.|:.:|.|.|..||.
  Fly   472 MVRHSLPLPETIIKSAKEDESVAPWLLGMHKKSLEAAELLKSDESDRETPTSDDTNTSYSAGSTH 536

Human   365 TTLTDLTSPTLP-TVTSVLTSVP----GNL--EGHEPH 395
                  .||... :::.:|...|    |:.  :||..|
  Fly   537 ------NSPISSFSISRLLFDAPPPAAGSAGGKGHHHH 568

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
LHX2NP_004780.3 LIM1_Lhx2 43..106 CDD:188853