DRSC/TRiP Functional Genomics Resources

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Protein Alignment NHERF2 and CG6688

DIOPT Version :10

Sequence 1:XP_054170405.1 Gene:NHERF2 / 9351 HGNCID:11076 Length:360 Species:Homo sapiens
Sequence 2:NP_651110.1 Gene:CG6688 / 42716 FlyBaseID:FBgn0039038 Length:424 Species:Drosophila melanogaster


Alignment Length:106 Identity:37/106 - (34%)
Similarity:57/106 - (53%) Gaps:4/106 - (3%)


- Green bases have known domain annotations that are detailed below.


Human   130 SHSSEAGKKDVSGPLRELR-PRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQ 193
            |.|:|.|:......:|.|| ||..   ...:.|||.|...|..|..::..|..|:|||..||:..
  Fly    10 STSNEDGQHGDGSSVRLLRIPRAA---PAMENYGFQLTRSKWDPYPWVCEVAAGTPAALCGLKPG 71

Human   194 DRLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETDE 234
            |.::||||.:|.|||.:|:...:|:::|...:|..:.|.|:
  Fly    72 DCVLEVNGNDVLGLRVSEIAKMVKSQKDCVTILCWNSECDK 112

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NHERF2XP_054170405.1 PDZ_NHERF-like 10..89 CDD:467249
PDZ_NHERF-like 150..229 CDD:467249 27/78 (35%)
EBP50_C 232..360 CDD:462654 1/3 (33%)
CG6688NP_651110.1 PDZ_canonical 25..104 CDD:483948 30/81 (37%)
RING-HC_SIAHs 143..179 CDD:438233
Blue background indicates that the domain is not in the aligned region.

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