Protein Alignment NDST3 and sfl

DIOPT Version :10

• Sequence 1: XP_016864328.1
• Gene: NDST3 / 9348
• HGNCID: 7682
• Length: 899
• Species: Homo sapiens
• Sequence 2: NP_001401031.1
• Gene: sfl / 38736
• FlyBaseID: FBgn0020251
• Length: 1129
• Species: Drosophila melanogaster
• Alignment Length: 858
• Identity: 474/858 - (55%)
• Similarity: 608/858 - (70%)
• Gaps: 39/858 - (4%)

Human    12 QRTVILLATFCMVSIIISAYY----LYSGYKQENELSETASEVDCGDL----QHL------PYQL 62
            :|.|:.|....||||....:|    :::|..|.:  :..|..::|..:    :|:      |...
  Fly   171 RRCVLALLAITMVSIFYYTHYVDTGVFNGLIQRD--THPAPIINCRMINSGGKHIRNASPAPDHR 233

Human    63 MEVKAMKLFDASRTDPTVLVFVESQYSSLGQDIIMILESSRFQYHIEIAPGKGDLPVLIDKMKGK 127
            .|.:.       |.||.||||||:.||.||:||..:|..:|.:|.||:| || .||||.:..||:
  Fly   234 SEARL-------RIDPKVLVFVETTYSGLGRDIAELLVYNRIKYKIEVA-GK-SLPVLTNLDKGR 289

Human   128 YILIIYENILKYINMDSWNRSLLDKYCVEYGVGVIGFHKTSEKSVQSFQLKGFPFSIYGNLAVKD 192
            |.:|::||:.||:|||.|||.||||||.||.||::||...||:::...||:.||..:..||.::|
  Fly   290 YGVIVFENLDKYLNMDKWNRELLDKYCREYSVGIVGFVSPSEETLVGAQLRDFPLFVNTNLRLRD 354

Human   193 CCINPHSPLIRVTKSSKLEKGSLPGTDWTVFQINHSAYQPVIFAKVKTPENLSPSISKGAF-YAT 256
            ..:||.|.::|:|::.:...|:|||.||.|||.|||.|:||.:|:..|.|..:.|:.:... ..|
  Fly   355 ASLNPLSSVLRLTRAGETAWGALPGDDWAVFQHNHSTYEPVEWAQRNTQEYPADSVGQVQLPLTT 419

Human   257 IIHDLGLHDGIQRVLFGNNLNFWLHKLIFIDAISFLSGKRLTLSLDRYILVDIDDIFVGKEGTRM 321
            ::.|.|..|||||||||::|.||||:|:|:||:|:||..:|:|:|:|.|||||||||||::|||:
  Fly   420 VLQDRGQLDGIQRVLFGSSLRFWLHRLVFLDALSYLSHGQLSLNLERMILVDIDDIFVGEKGTRL 484

Human   322 NTNDVKALLDTQNLLRAQITNFTFNLGFSGKFYHTGTEEEDEGDDCLLGSVDEFWWFPHMWSHMQ 386
            ..:||:||:.||..:.|.:..|.||||||||:||.||.||:.|||.||.:|.||.||.|||.|.|
  Fly   485 RPDDVRALIATQKNIAAMVPGFRFNLGFSGKYYHHGTREENLGDDFLLQNVQEFNWFSHMWKHQQ 549

Human   387 PHLFHNESSLVEQMILNKKFALEHGIPTDMGYAVAPHHSGVYPVHVQLYEAWKKVWNIKITSTEE 451
            |||:.|.:.|:.:|.||..||::|.||||.||:::||||||||.|..||.|||||||:|:|||||
  Fly   550 PHLYDNLTLLMAEMHLNYAFAVDHNIPTDSGYSISPHHSGVYPAHELLYMAWKKVWNVKVTSTEE 614

Human   452 YPHLKPARYRRGFIHKNIMVLPRQTCGLFTHTIFYKEYPGGPKELDKSIQGGELFFTVVLNPISI 516
            ||||:|||.||||||:||||||||||||||||::...||||..:||:||||||||.|:|.|||:|
  Fly   615 YPHLRPARLRRGFIHRNIMVLPRQTCGLFTHTMYIDRYPGGRDKLDESIQGGELFQTIVYNPINI 679

Human   517 FMTHLSNYGNDRLGLYTFVNLANFVKSWTNLRLQTLPPVQLAHKYFELFPDQKDPLWQNPCDDKR 581
            ||||:||||:|||.||||.::..|::.||||:|.:.||||||..||.|.|::.||:|.|||||.|
  Fly   680 FMTHMSNYGSDRLALYTFQSVIKFLQCWTNLKLASAPPVQLAEMYFRLHPEEVDPVWGNPCDDVR 744

Human   582 HRDIWSKEKTCDRLPKFLVIGPQKTGTTALYLFLVMHPSILSNSPSPKTFEEVQFFNRNNYHRGI 646
            |:.||||.|.||.||||||||||||||||||.||.||.||.||..||:|||||||||.|||:||:
  Fly   745 HKKIWSKTKNCDSLPKFLVIGPQKTGTTALYTFLSMHGSIASNIASPETFEEVQFFNGNNYYRGL 809

Human   647 DWYMDFFPVPSNVTTD-----------FLFEKSANYFHSEEAPKRAASLVPKAKIITILIDPSDR 700
            ||||||||..|...|.           |:|||||.||..|..|||:.:|:|.|||:||||.|:.|
  Fly   810 DWYMDFFPSESLPNTSSPMPTQLGSPRFMFEKSATYFDGEAVPKRSHALLPHAKIVTILISPAKR 874

Human   701 AYSWYQHQRSHEDPAALKFSFYEVISAGPRAPSELRALQKRCLVPGWYASHIERWLVYFPPFQLL 765
            |||||||||||.|..|..:|||:||:|...||..|:.|:.|||.||.||.|:|.||.|:|..||.
  Fly   875 AYSWYQHQRSHGDVIANNYSFYQVITASDSAPRALKDLRNRCLNPGKYAQHLEHWLAYYPAQQLH 939

Human   766 IIDGQQLRTDPATVMDEVQKFLGVLPHYNYSEALTFDSHKGFWCQLLEEGKTKCLGKSKGRKYPP 830
            ||||:|||.:|..||:|:|:||.:.|..:||..|.:|..|||:||.:.|.:.|||||||||:||.
  Fly   940 IIDGEQLRLNPIDVMNELQRFLKIQPLLDYSNHLRYDVKKGFYCQAVSEKRNKCLGKSKGRQYPA 1004

Human   831 MDSDDISVKLLSR 843
            |  |:.|.|||.|
  Fly  1005 M--DERSAKLLQR 1015

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NDST3	XP_016864328.1	HSNSD	76..506	CDD:463450	246/430 (57%)
		Sulfotransfer_1	595..824	CDD:425820	143/239 (60%)
sfl	NP_001401031.1	HSNSD	240..669	CDD:463450	246/430 (57%)
		Sulfotransfer_1	758..1017	CDD:425820	156/260 (60%)