DRSC/TRiP Functional Genomics Resources

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Protein Alignment ORAI3 and orai1a

DIOPT Version :10

Sequence 1:NP_689501.1 Gene:ORAI3 / 93129 HGNCID:28185 Length:295 Species:Homo sapiens
Sequence 2:XP_695046.5 Gene:orai1a / 566671 ZFINID:ZDB-GENE-110721-1 Length:225 Species:Danio rerio


Alignment Length:257 Identity:145/257 - (56%)
Similarity:182/257 - (70%) Gaps:47/257 - (18%)


- Green bases have known domain annotations that are detailed below.


Human    39 MGASQHSLRALSWRRLYLSRAKLKASSRTSALLSGFAMVAMVEVQLESDHEYPPGLLVAFSACTT 103
            |..::|||:|||||:||||||||||:|||||||||||||||||.|||.||.||||||:|||||||
Zfish     1 MSLNEHSLQALSWRKLYLSRAKLKATSRTSALLSGFAMVAMVECQLEEDHNYPPGLLIAFSACTT 65

Human   104 VLVAVHLFALMVSTCLLPHIEAVSNIHNLNSVHQSPHQRLHRYVELAWGFSTALGTFLFLAEVVL 168
            |||||||||||:|||:||::|||||:|||||:.:|||:|:||::||||.|||.:||.||||||||
Zfish    66 VLVAVHLFALMISTCILPNLEAVSNVHNLNSIKESPHERMHRHIELAWAFSTVIGTLLFLAEVVL 130

Human   169 VGWVKFVPIGAPLDTPTPMVPTSRVPGTLAPVATSLSPASNLPRSSASAAPSQAEPACPPRQACG 233
            :.||||:|:             |:.|.|              .:.:.:.||..:|          
Zfish   131 LCWVKFLPL-------------SQTPVT--------------QKENVTQAPGISE---------- 158

Human   234 GGGAHGPGWQAAMASTAIMVPVGLVFVAFALHFYRSLVAHKTDRYKQELE---ELNRLQGEL 292
                   |..||:|||.||||..|||:.||:|||||||:|||:|..:|||   ::.::|.:|
Zfish   159 -------GKAAAIASTTIMVPFALVFIVFAVHFYRSLVSHKTERQHEELEVLAKITQMQNQL 213

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ORAI3NP_689501.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..23
Orai-1 48..276 CDD:462291 134/227 (59%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 204..238 3/33 (9%)
orai1aXP_695046.5 None
Blue background indicates that the domain is not in the aligned region.

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