DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ORAI3 and orai1b

DIOPT Version :10

Sequence 1:NP_689501.1 Gene:ORAI3 / 93129 HGNCID:28185 Length:295 Species:Homo sapiens
Sequence 2:NP_991163.1 Gene:orai1b / 402892 ZFINID:ZDB-GENE-050522-100 Length:222 Species:Danio rerio


Alignment Length:254 Identity:155/254 - (61%)
Similarity:181/254 - (71%) Gaps:51/254 - (20%)


- Green bases have known domain annotations that are detailed below.


Human    39 MGASQHSLRALSWRRLYLSRAKLKASSRTSALLSGFAMVAMVEVQLESDHEYPPGLLVAFSACTT 103
            |..|:|||:|||||:|||||||||||||||||||||||||||||||:::|:||||||:|||||||
Zfish     3 MSRSEHSLQALSWRKLYLSRAKLKASSRTSALLSGFAMVAMVEVQLDTNHDYPPGLLIAFSACTT 67

Human   104 VLVAVHLFALMVSTCLLPHIEAVSNIHNLNSVHQSPHQRLHRYVELAWGFSTALGTFLFLAEVVL 168
            |||||||||||||||:||:||||||:||||||.:|||:|:||::||||.|||.:||.||||||||
Zfish    68 VLVAVHLFALMVSTCILPNIEAVSNVHNLNSVKESPHERMHRHIELAWAFSTVIGTLLFLAEVVL 132

Human   169 VGWVKFVPIGAPLDTPTPMVPTSRVPGTLAPVATSLSPASNLPRSSASAAPSQAEPACPPRQACG 233
            :.||||:||          .|..:..||:                ||..|               
Zfish   133 LCWVKFLPI----------KPKDQKNGTV----------------SAGVA--------------- 156

Human   234 GGGAHGPGWQAAMASTAIMVPVGLVFVAFALHFYRSLVAHKTDRYKQELEELNRLQGEL 292
                      ||:.||:||||.||||:.||:|||||||:|||||..||||||..||.||
Zfish   157 ----------AAITSTSIMVPFGLVFIVFAVHFYRSLVSHKTDRQFQELEELEDLQNEL 205

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ORAI3NP_689501.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..23
Orai-1 48..276 CDD:462291 137/227 (60%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 204..238 3/33 (9%)
orai1bNP_991163.1 Orai-1 12..189 CDD:462291 137/227 (60%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.