Protein Alignment ORAI3 and Orai3

DIOPT Version :10

• Sequence 1: NP_689501.1
• Gene: ORAI3 / 93129
• HGNCID: 28185
• Length: 295
• Species: Homo sapiens
• Sequence 2: NP_940816.1
• Gene: Orai3 / 269999
• MGIID: 3039586
• Length: 290
• Species: Mus musculus
• Alignment Length: 297
• Identity: 262/297 - (88%)
• Similarity: 271/297 - (91%)
• Gaps: 9/297 - (3%)

Human     1 MKGGEGDAGEQAPLNPEGESPAGSATYREFVHRGYLDLMGASQHSLRALSWRRLYLSRAKLKASS 65
            |||||||.|||||||||.:||||||||||||||||||||||||||||||||||||||||||||||
Mouse     1 MKGGEGDTGEQAPLNPEVDSPAGSATYREFVHRGYLDLMGASQHSLRALSWRRLYLSRAKLKASS 65

Human    66 RTSALLSGFAMVAMVEVQLESDHEYPPGLLVAFSACTTVLVAVHLFALMVSTCLLPHIEAVSNIH 130
            ||||||||||||||||||||:||||||||||||||||||||||||||||||||||||||||||||
Mouse    66 RTSALLSGFAMVAMVEVQLENDHEYPPGLLVAFSACTTVLVAVHLFALMVSTCLLPHIEAVSNIH 130

Human   131 NLNSVHQSPHQRLHRYVELAWGFSTALGTFLFLAEVVLVGWVKFVPIGAPLDTPTPMVPTSRVPG 195
            ||||||||||||||||||||||||||||||||||||||||||||||||||:..|.|:||.|:||
Mouse   131 NLNSVHQSPHQRLHRYVELAWGFSTALGTFLFLAEVVLVGWVKFVPIGAPMGKPAPVVPMSQVP- 194

Human   196 TLAPVATSLSPASNLPRSSASAAPSQAEP--ACPPRQACGGGGAHGPGWQAAMASTAIMVPVGLV 258
               ||..|||.||||..||||...|| :|  ||||||.|  ..||||||||||||||||||||||
Mouse   195 ---PVTVSLSLASNLTPSSASITTSQ-QPSKACPPRQVC--DSAHGPGWQAAMASTAIMVPVGLV 253

Human   259 FVAFALHFYRSLVAHKTDRYKQELEELNRLQGELQAV 295
            |:|||||||||||||||||:|||||||:|||||||||
Mouse   254 FMAFALHFYRSLVAHKTDRHKQELEELSRLQGELQAV 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ORAI3	NP_689501.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23		18/21 (86%)
		Orai-1	48..276	CDD:462291	199/229 (87%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	204..238		20/35 (57%)
Orai3	NP_940816.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21		16/19 (84%)
		Orai-1	48..271	CDD:462291	199/229 (87%)