Protein Alignment MARS2 and Mars2

DIOPT Version :10

• Sequence 1: NP_612404.1
• Gene: MARS2 / 92935
• HGNCID: 25133
• Length: 593
• Species: Homo sapiens
• Sequence 2: NP_780648.1
• Gene: Mars2 / 212679
• MGIID: 2444136
• Length: 586
• Species: Mus musculus
• Alignment Length: 593
• Identity: 509/593 - (85%)
• Similarity: 537/593 - (90%)
• Gaps: 7/593 - (1%)

Human     1 MLRTSVLRLLGRTGASRLSLLEDFGPRYYSSGSLSAGDDACDVRAYFTTPIFYVNAAPHIGHLYS 65
            |||.....:|.||...|       |.|.|.|.|.||..||.:.||||||||||||||||||||||
Mouse     1 MLRQCARWVLTRTRFGR-------GCRRYGSCSPSASGDAGEARAYFTTPIFYVNAAPHIGHLYS 58

Human    66 ALLADALCRHRRLRGPSTAATRFSTGTDEHGLKIQQAAATAGLAPTELCDRVSEQFQQLFQEAGI 130
            ||||||||||||||.|.:|:|||||||||||||||||||||||||.|||||||.||.|||:||.|
Mouse    59 ALLADALCRHRRLRVPGSASTRFSTGTDEHGLKIQQAAATAGLAPIELCDRVSAQFLQLFREADI 123

Human   131 SCTDFIRTTEARHRVAVQHFWGVLKSRGLLYKGVYEGWYCASDECFLPEAKVTQQPGPSGDSFPV 195
            |.||||||||||||||||||||||::|||||||:|||||||||||||||||||:|.|||||..||
Mouse   124 SSTDFIRTTEARHRVAVQHFWGVLEARGLLYKGIYEGWYCASDECFLPEAKVTRQVGPSGDPCPV 188

Human   196 SLESGHPVSWTKEENYIFRLSQFRKPLQRWLRGNPQAITPEPFHHVVLQWLDEELPDLSVSRRSS 260
            ||||||||||||||||||:|||||:||||||..|||||||||||..|||||:|||||||||||||
Mouse   189 SLESGHPVSWTKEENYIFKLSQFREPLQRWLGNNPQAITPEPFHQAVLQWLEEELPDLSVSRRSS 253

Human   261 HLHWGIPVPGDDSQTIYVWLDALVNYLTVIGYPNAEFKSWWPATSHIIGKDILKFHAIYWPAFLL 325
            |||||||||||||||||||||||||||||:|||:|:||||||||||||||||||||||||||.||
Mouse   254 HLHWGIPVPGDDSQTIYVWLDALVNYLTVVGYPDADFKSWWPATSHIIGKDILKFHAIYWPALLL 318

Human   326 GAGMSPPQRICVHSHWTVCGQKMSKSLGNVVDPRTCLNRYTVDGFRYFLLRQGVPNWDCDYYDEK 390
            |||:.||.||.|||||||.||||||||||||||||||:|||||||||||||||||||||||||||
Mouse   319 GAGLRPPHRIYVHSHWTVSGQKMSKSLGNVVDPRTCLDRYTVDGFRYFLLRQGVPNWDCDYYDEK 383

Human   391 VVKLLNSELADALGGLLNRCTAKRINPSETYPAFCTTCFPSEPGLVGPSVRAQAEDYALVSAVAT 455
            |||||:||||||||||||||||.|||||.|||:||..||||||||.|||||.||||||||:||||
Mouse   384 VVKLLDSELADALGGLLNRCTAYRINPSGTYPSFCAACFPSEPGLTGPSVRVQAEDYALVTAVAT 448

Human   456 LPKQVADHYDNFRIYKALEAVSSCVRQTNGFVQRHAPWKLNWESPVDAPWLGTVLHVALECLRVF 520
            |||.||.:|::|:||||||||||||||||||||||||||||||||.|||||||||||||||||||
Mouse   449 LPKLVAGYYNDFQIYKALEAVSSCVRQTNGFVQRHAPWKLNWESPEDAPWLGTVLHVALECLRVF 513

Human   521 GTLLQPVTPSLADKLLSRLGVSASERSLGELYFLPRFYGHPCPFEGRRLGPETGLLFPRLDQSRT 585
            |||||||||:||||||||||||.:||.||||||||||||||||||||:|||:|||||||||||||
Mouse   514 GTLLQPVTPNLADKLLSRLGVSTTERGLGELYFLPRFYGHPCPFEGRKLGPDTGLLFPRLDQSRT 578

Human   586 WLVKAHRT 593
            .|||||||
Mouse   579 RLVKAHRT 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MARS2	NP_612404.1	MetG	44..581	CDD:439913	480/536 (90%)
		'HIGH' region	52..62		9/9 (100%)
		'KMSKS' region	347..351		3/3 (100%)
Mars2	NP_780648.1	MetG	37..574	CDD:439913	480/536 (90%)
		'HIGH' region	45..55		9/9 (100%)
		'KMSKS' region	340..344		3/3 (100%)