Protein Alignment REEP6 and ReepA

DIOPT Version :10

• Sequence 1: NP_001316485.1
• Gene: REEP6 / 92840
• HGNCID: 30078
• Length: 211
• Species: Homo sapiens
• Sequence 2: NP_001188988.1
• Gene: ReepA / 37643
• FlyBaseID: FBgn0261564
• Length: 716
• Species: Drosophila melanogaster
• Alignment Length: 220
• Identity: 57/220 - (25%)
• Similarity: 90/220 - (40%)
• Gaps: 66/220 - (30%)

Human    52 YGASLLCNLI----------------------GFVYPAYASIKAIESPSKDDDTVWLTYWVVYAL 94
            :..:.:|:||                      |.:||||||.||:.:....:...|:.||:|:|.
  Fly   130 FNTACICSLIVIFLAPRTCAQSLLFPAFRLFCGTLYPAYASYKAVRTKDVKEYVKWMMYWIVFAF 194

Human    95 FGLAEFFSDLLLSWFPFYYVGKCAFLLFCMAPRPWNGALMLYQRVVRPLFLRHHGAVDRIMNDLS 159
            |...|.|:|:.:||.||||..|.|.:.:.::|.. .|:..||::.|.|:..||...:|..:|...
  Fly   195 FTCIETFTDIFISWLPFYYEVKVALVFWLLSPAT-KGSSTLYRKFVHPMLTRHEQEIDEYVNQAK 258

Human   160 GRALDA-----AAGIT--------------RNVLQVLARS----------------------RAG 183
            .|...|     :.|:.              .|::|.:.||                      .:.
  Fly   259 ERGYSAVLQLGSKGVNYATNVLMQTAIKGGGNLVQTIKRSYSLSDLSEPDMHRTQDELDDVMMSS 323

Human   184 ITPVAVAGPSTPLEAD-LKP-SQTP 206
            :|..||...||...|. |:| :|||
  Fly   324 MTSSAVVMRSTATGARLLRPRNQTP 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
REEP6	NP_001316485.1	TB2_DP1_HVA22	66..143	CDD:460820	29/76 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	190..211		8/19 (42%)
ReepA	NP_001188988.1	TB2_DP1_HVA22	166..242	CDD:460820	29/76 (38%)