Protein Alignment REEP6 and Reepl1

DIOPT Version :10

• Sequence 1: NP_001316485.1
• Gene: REEP6 / 92840
• HGNCID: 30078
• Length: 211
• Species: Homo sapiens
• Sequence 2: NP_572730.1
• Gene: Reepl1 / 32103
• FlyBaseID: FBgn0030313
• Length: 240
• Species: Drosophila melanogaster
• Alignment Length: 226
• Identity: 50/226 - (22%)
• Similarity: 85/226 - (37%)
• Gaps: 68/226 - (30%)

Human    48 LLFGYGASLLCNLIGFVYPAYASIKAIESP--SKDDDTVWLTYWVVYALFGLAEFFSDLLLSWFP 110
            :::.....:|..|:|..|||:||.|.::|.  |.:|...||.||:.|.::...::|:..||::.|
  Fly     1 MIYAIVIHILSLLVGCFYPAFASYKILKSQNCSVNDLRGWLIYWIAYGVYVAFDYFTAGLLAFIP 65

Human   111 FYYVGKCAFLLFCMAPRPWNGALMLYQRVVRPLFLRHHGAVDRIMNDLSGRALDAAAGITRNVLQ 175
            .....| ..|||.|.|....|:.::|:..:|......  :.|:::..::   |:....:.:.|..
  Fly    66 LLSEFK-VLLLFWMLPSVGGGSEVIYEEFLRSFSCNE--SFDQVLGRIT---LEWGELVWQQVCS 124

Human   176 VLA---------------RSRAGITP---------VA--------------------VAGPSTPL 196
            ||:               |....|||         :|                    |.|.:..|
  Fly   125 VLSHLMVLADRYLLPSGHRPALQITPSIEDLVNDAIAKRQLEEKRKQMGNLSDTINEVLGENIDL 189

Human   197 EADL----------------KPSQTPQPKDK 211
            ..||                ||.:.|.|..|
  Fly   190 NMDLLHGSESDLLVIKEPISKPKERPIPPPK 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
REEP6	NP_001316485.1	TB2_DP1_HVA22	66..143	CDD:460820	26/78 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	190..211		8/36 (22%)
Reepl1	NP_572730.1	TB2_DP1_HVA22	19..97	CDD:460820	26/78 (33%)