| Sequence 1: | NP_620711.3 | Gene: | DNER / 92737 | HGNCID: | 24456 | Length: | 737 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_499014.1 | Gene: | glp-1 / 176286 | WormBaseID: | WBGene00001609 | Length: | 1295 | Species: | Caenorhabditis elegans |
| Alignment Length: | 419 | Identity: | 127/419 - (30%) |
|---|---|---|---|
| Similarity: | 176/419 - (42%) | Gaps: | 103/419 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Human 293 IVALRLTLVVKVSTCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCE-EYDACQRK 356
Human 357 PCQNNASCIDANEKQD--GSNFTCVCL-----------------PGYTGELCQ----SKIDYCIL 398
Human 399 DPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGP 463
Human 464 TCAQLIDFCAL--SPCAHGTC---RSVGTSYKCLCDPGYHGLYCEEEYNECL-SAPCLNAATCRD 522
Human 523 LVNGYECVCLAEYKGTHCELYKDPCANVSCLN--------------------------------- 554
Human 555 -----------------GATCDSDG--LNGTCICAPGFTGEECDI--------DINECDSNPCHH 592
Human 593 GGSCLDQPN-GYNCHCPHGWVGANCEIHL 620 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| DNER | NP_620711.3 | Interaction with NOTCH1. /evidence=ECO:0000250 | 44..133 | ||
| EGF_CA | 393..428 | CDD:238011 | 15/34 (44%) | ||
| EGF_CA | 431..465 | CDD:238011 | 10/33 (30%) | ||
| EGF_CA | 469..503 | CDD:238011 | 14/38 (37%) | ||
| EGF_CA | 507..541 | CDD:238011 | 13/34 (38%) | ||
| EGF_CA | 581..617 | CDD:238011 | 18/36 (50%) | ||
| Interaction with AP1G1 and somatodendritic targeting. /evidence=ECO:0000250 | 677..680 | ||||
| glp-1 | NP_499014.1 | EGF_CA | 118..152 | CDD:238011 | 15/34 (44%) |
| EGF_CA | 155..190 | CDD:238011 | 10/34 (29%) | ||
| EGF_CA | 232..269 | CDD:238011 | 13/36 (36%) | ||
| EGF_CA | 369..406 | CDD:238011 | 18/36 (50%) | ||
| EGF_CA | 451..479 | CDD:238011 | |||
| NL | 489..526 | CDD:197463 | |||
| Notch | 533..568 | CDD:278494 | |||
| Notch | 573..608 | CDD:278494 | |||
| NOD | 612..661 | CDD:284282 | |||
| NODP | 698..755 | CDD:284987 | |||
| ANK repeat | 921..959 | CDD:293786 | |||
| ANK | 926..1054 | CDD:238125 | |||
| Ank_5 | 949..1002 | CDD:290568 | |||
| ANK | 956..1127 | CDD:238125 | |||
| ANK repeat | 961..992 | CDD:293786 | |||
| ANK repeat | 994..1028 | CDD:293786 | |||
| Ank_2 | 999..1105 | CDD:289560 | |||
| ANK repeat | 1030..1061 | CDD:293786 | |||
| ANK repeat | 1071..1105 | CDD:293786 | |||
| Ank_2 | 1079..1171 | CDD:289560 | |||
| ANK repeat | 1107..1138 | CDD:293786 | |||
| ANK repeat | 1140..1170 | CDD:293786 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D7525at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 2.010 | |||||