Protein Alignment CYTH2 and gea1

DIOPT Version :10

• Sequence 1: XP_006723535.1
• Gene: CYTH2 / 9266
• HGNCID: 9502
• Length: 421
• Species: Homo sapiens
• Sequence 2: NP_596613.1
• Gene: gea1 / 2540746
• PomBaseID: SPBC211.03C
• Length: 1462
• Species: Schizosaccharomyces pombe
• Alignment Length: 292
• Identity: 85/292 - (29%)
• Similarity: 139/292 - (47%)
• Gaps: 33/292 - (11%)

Human    51 LLVEIQRLREELSEAMSEVEGLEANEGSKTLQRNRK----MAMGRKKFNMDPKKGIQFLVENELL 111
            ||..|....|.|....::......::.:|||..::|    :..|.:.||..|..||.||.::.::
pombe   512 LLNFIYYFHEHLQPCYNDPNNTFKDDVAKTLIESKKRKAIIIEGAELFNESPSDGIAFLTQHSII 576

Human   112 Q--NTPEEIARFLYKGEGLNKTAIGDYLGEREELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFR 174
            :  :.|..|..|.:....|:|..:|::|.:..  |..:|:||:...:|....:.:|||..|.|||
pombe   577 KQSDNPTCIVEFFHSTNRLSKRVLGEFLTKGS--NSHILNAFISAFDFKGKRIDEALRLLLQSFR 639

Human   175 LPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRD--KPGLERFVA 237
            ||||:|.|:|::|.|:..|...||....|.|..:|||:::|||||..||||::.  :..|:.|..
pombe   640 LPGESQLIERVLETFSHYYMSANPDSMSSKDAAFVLSYSIIMLNTDQHNPNIKSQRRMTLDDFCR 704

Human   238 MNRGINEGGDLPEELLRNLYDSIRNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVK---TWK 299
            ..||:|:|.|.....|..:|.:|:.....:.|:...:|:..:.      | .||...||   .:|
pombe   705 NVRGVNDGQDFDRNFLSEIYKAIKENEIIVAEEHDTELSFLYI------W-SKLQQSVKITEPFK 762

Human   300 RR-------------WFILTDNCLYYFEYTTD 318
            |.             |..:....:|.|...|:
pombe   763 RSSSNVHDKIVFLEVWKSIMAALIYVFSTATE 794

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYTH2	XP_006723535.1	Sec7	83..265	CDD:460178	64/189 (34%)
		PH_GRP1-like	280..399	CDD:269954	11/55 (20%)
gea1	NP_596613.1	Sec7_N	287..476	CDD:463703
		Sec7	548..732	CDD:460178	63/185 (34%)