Protein Alignment CYTH3 and Cyth3

DIOPT Version :9

• Sequence 1: NP_004218.1
• Gene: CYTH3 / 9265
• HGNCID: 9504
• Length: 399
• Species: Homo sapiens
• Sequence 2: NP_035312.3
• Gene: Cyth3 / 19159
• MGIID: 1335107
• Length: 399
• Species: Mus musculus
• Alignment Length: 399
• Identity: 395/399 - (98%)
• Similarity: 396/399 - (99%)
• Gaps: 0/399 - (0%)

Human     1 MDEDGGGEGGGVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEESKTTQ 65
            |||.||||||.||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse     1 MDEGGGGEGGSVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEESKTTQ 65

Human    66 RNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDEFNIKV 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:|||||
Mouse    66 RNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDDFNIKV 130

Human   131 LQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVLSF 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   131 LQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVLSF 195

Human   196 AIIMLNTSLHNHNVRDKPTAERFIAMNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTH 260
            ||||||||||||||||||||||||.||||||||||||||||||||||||||||||||||||||||
Mouse   196 AIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTH 260

Human   261 TFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPN 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   261 TFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPN 325

Human   326 CFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRDPFYDMLAT 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   326 CFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRDPFYDMLAT 390

Human   391 RKRRIANKK 399
            |||||||||
Mouse   391 RKRRIANKK 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYTH3	NP_004218.1	Sec7	66..248	CDD:396096	179/181 (99%)
		PH_GRP1-like	263..382	CDD:269954	118/118 (100%)
		C-terminal autoinhibitory region. /evidence=ECO:0000269|PubMed:23940353	391..399		7/7 (100%)
Cyth3	NP_035312.3	Sec7	66..248	CDD:396096	179/181 (99%)
		PH_GRP1-like	263..382	CDD:269954	118/118 (100%)
		Phosphatidylinositol 3,4,5-trisphosphate binding	273..280		6/6 (100%)
		C-terminal autoinhibitory region	391..399		7/7 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83956234
Domainoid	1	1.000	368	1.000	Domainoid score	I12633
eggNOG	1	0.900	-	-		E1_COG5307
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3116
Inparanoid	1	1.050	802	1.000	Inparanoid score	I7912
Isobase	1	0.950	-	0	Normalized mean entropy	S1799
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG57553
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000619
OrthoInspector	1	1.000	-	-		oto114228
orthoMCL	1	0.900	-	-		OOG6_103039
Panther	1	1.100	-	-	LDO	PTHR10663
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5313
SonicParanoid	1	1.000	-	-		X419
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	18	18.240