Protein Alignment STK17B and CaMKI

DIOPT Version :9

• Sequence 1: NP_004217.1
• Gene: STK17B / 9262
• HGNCID: 11396
• Length: 372
• Species: Homo sapiens
• Sequence 2: NP_524622.1
• Gene: CaMKI / 43792
• FlyBaseID: FBgn0016126
• Length: 405
• Species: Drosophila melanogaster
• Alignment Length: 367
• Identity: 111/367 - (30%)
• Similarity: 174/367 - (47%)
• Gaps: 75/367 - (20%)

Human    23 IKMENFNNFYILTSKELGRGKFAVVRQCISK-STGQEYAAKFL-KKRRRGQDCRAEILHEIAVLE 85
            :.:|...|.:.|    ||.|.|:.||...|| |.|:.:|.|.: ||..:|::...|  :||.||.
  Fly    25 VSIEEKYNLHGL----LGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKEESLE--NEIRVLR 83

Human    86 LAKS------C--------PRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVS--END 134
            ...:      |        |.::.|.|.||:.|::.|::|...|||:|.    .:.|..|  |.|
  Fly    84 RFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFD----RIVEKGSYTEKD 144

Human   135 VIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIV--DFGMSRK-----IGHACEL 192
            ...||:||||.|.|:|:..:||.||||:|:|..|  |..|.||:  |||:|:.     :..||
  Fly   145 ASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYS--PDDDSKIMISDFGLSKMEDSGIMATAC-- 205

Human   193 REIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEE 257
                |||.|:|||:|...|...|.|:|:||:|:|:||....||..|::...:..|.:.:.::...
  Fly   206 ----GTPGYVAPEVLAQKPYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGDFEFDSP 266

Human   258 TFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWL------------------------QQWD- 297
            .:..:|:.|..||::|:....|||.|.:..|.|:|:                        .:|.
  Fly   267 YWDEISESAKHFIKNLMCVTVEKRYTCKQALGHAWISGNEASSRNIHGTVSEQLKKNFAKSRWKQ 331

Human   298 -------FENLFHPEETSSSSQTQDHSVRSSEDKTSKSSCNG 332
                   ...:......|:|:...|.|..|::|.|:.::..|
  Fly   332 AYYAATVIRQMQRMALNSNSNANFDSSNSSNQDSTTPTAATG 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STK17B	NP_004217.1	STKc_DRAK2	24..293	CDD:271100	101/293 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	305..362		8/28 (29%)
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	101/291 (35%)
		S_TKc	31..302	CDD:214567	100/288 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810