Protein Alignment DHRS3 and CG13833

DIOPT Version :10

• Sequence 1: NP_004744.2
• Gene: DHRS3 / 9249
• HGNCID: 17693
• Length: 302
• Species: Homo sapiens
• Sequence 2: NP_651111.1
• Gene: CG13833 / 42718
• FlyBaseID: FBgn0039040
• Length: 321
• Species: Drosophila melanogaster
• Alignment Length: 285
• Identity: 79/285 - (27%)
• Similarity: 148/285 - (51%)
• Gaps: 18/285 - (6%)

Human     6 LGALVMFPLQMIYLVVKAAVGLVLPAKL------RDLSRENVLITGGGRGIGRQLAREFAERGAR 64
            :|...:.||    |::.|.:|.:: |||      :.::.|..::||.|.|:||.::.|.|::|..
  Fly    19 IGLAAITPL----LILVALLGRLI-AKLCWCSAPKSIAGEVAVVTGAGHGLGRAISLELAKKGCH 78

Human    65 KIVLWGRTEKCLKETTEEIRQM-GTECHYFICDVGNREEVYQTAKAVREKVGDITILVNNAAVVH 128
             |.:........::|.::|:.: ......:..:|.|.:::.:....|.|::|.:|:|||||.|:.
  Fly    79 -IAVVDINVSGAEDTVKQIQDIYKVRAKAYKANVTNYDDLVELNSKVVEEMGPVTVLVNNAGVMM 142

Human   129 GKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKA 193
            .:::.:.|...:....::|....|||...|||:|.||:.|.||.::|:..:..:|.:..|.|:|:
  Fly   143 HRNMFNPDPADVQLMINVNLTSHFWTKLVFLPKMKELRKGFIVTISSLAGVFPLPYSATYTTTKS 207

Human   194 SAFAFMESL--TLGLLDCPGVSATTVLP--FHTSTEMFQ-GMRVRFPNLFPPLKPETVARRTVEA 253
            .|.|.|.:|  .|.|.:...:..|||||  ..|::::.| ...:.|.:::|....|.||:|.|..
  Fly   208 GALAHMRTLRMELDLENQKDIHVTTVLPSFLRTNSDVTQLTHTIGFGDVYPLFTGEEVAQRIVAG 272

Human   254 VQLNQALLLLPWTMHALVILKSILP 278
            :...:|.:.:|.....|..:..|||
  Fly   273 MVRGEAEITVPGMACLLYRVILILP 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DHRS3	NP_004744.2	17beta-HSDXI-like_SDR_c	53..281	CDD:187598	63/232 (27%)
CG13833	NP_651111.1	YqjQ	49..305	CDD:440069	70/250 (28%)