Protein Alignment DHRS3 and CG15629

DIOPT Version :10

• Sequence 1: NP_004744.2
• Gene: DHRS3 / 9249
• HGNCID: 17693
• Length: 302
• Species: Homo sapiens
• Sequence 2: NP_608859.1
• Gene: CG15629 / 33679
• FlyBaseID: FBgn0031630
• Length: 325
• Species: Drosophila melanogaster
• Alignment Length: 309
• Identity: 107/309 - (34%)
• Similarity: 172/309 - (55%)
• Gaps: 15/309 - (4%)

Human     2 VWKRLGALVMFPLQMIYLVVKAAVGLVLP---AKLRDLSRENVLITGGGRGIGRQLAREFAERGA 63
            :::.|..|::|.::.:|.|:::....:||   .||:|:|.:.|||||||.|:||.:|..||...|
  Fly    17 IYQFLLDLLVFTIKSVYYVLESIYYSLLPQRFRKLKDISGQVVLITGGGGGVGRLIALNFARLQA 81

Human    64 RKIVLWGRTEKCLKETTEEIRQMGTE-CHYFICDVGNREEVYQTAKAVREKVGDITILVNNAAVV 127
            | ||:|...::.:|.|.:.:.:.|.: |..::.|:.:||::||.|..|.|:||.:.||:|||.:|
  Fly    82 R-IVIWDINQEAIKTTVDLLAKHGYDNCKGYVVDISDREQIYQRASQVTEEVGPVDILINNAGIV 145

Human   128 HGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSK 192
            ..|...:..|..:..:.:||.:..:||.|||||.|:....||||.:.||..:....|..||..:|
  Fly   146 CCKPFWELHDRVIQNTYNINIISHYWTVKAFLPHMMRNNRGHIVTVGSVTGMLGTYGCSDYAATK 210

Human   193 ASAFAFMESLTLGLLDCPG---VSATTVLPFHTSTEMFQGMRVRFPNLFPPLKPETVARRTVEAV 254
            .:...|.||| |..|...|   :..:.:.|::.:|.||.|:|   |.:.|.|:|:.||.|...||
  Fly   211 YACIGFHESL-LTDLKAHGYDQIQMSLICPYYINTGMFSGVR---PRMMPMLEPQYVADRIENAV 271

Human   255 QLNQALLLLPWTMHALVILKSILPQAALEEI--HKFSGTYTCMNTFKGR 301
            :.|:...:||.::..|..||.:||.....|:  ....|..:.| .|:||
  Fly   272 RCNEVWCVLPNSIRLLTPLKCLLPAKMCWELMSRVIRGPESMM-MFQGR 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DHRS3	NP_004744.2	17beta-HSDXI-like_SDR_c	53..281	CDD:187598	80/231 (35%)
CG15629	NP_608859.1	17beta-HSDXI-like_SDR_c	58..298	CDD:187598	90/244 (37%)