Protein Alignment CHMP4C and CG5498

DIOPT Version :10

• Sequence 1: NP_689497.1
• Gene: CHMP4C / 92421
• HGNCID: 30599
• Length: 233
• Species: Homo sapiens
• Sequence 2: NP_730525.2
• Gene: CG5498 / 40250
• FlyBaseID: FBgn0027565
• Length: 448
• Species: Drosophila melanogaster
• Alignment Length: 207
• Identity: 46/207 - (22%)
• Similarity: 84/207 - (40%)
• Gaps: 15/207 - (7%)

Human    24 EALVRLRETEEMLGKKQEYLENRIQREIALAKKHGTQNKRAALQALKRKKR-FEKQLTQIDGTLS 87
            :|:..|:.|:..|.|:.|.||..|:......:::..:|||...:...||:. .||...:....|.
  Fly   244 QAVHNLQNTQAQLLKQLEDLEEEIKVNDDKVRQYMKENKRQMAKTYLRKRHLLEKNHERRSLALH 308

Human    88 TIEFQREALENSHTNTEVLRNMGFAAKAMKSVHENMDL--NKIDDLMQEITEQQDIAQEISEAFS 150
            .||....:::.:..:..||......:..:|.|..|..|  :.:|:::.::.:..|..:|:.:..|
  Fly   309 NIESLLSSVDEAQNSGVVLDAYKIGSNTLKKVLSNSGLKYDNVDEVLADVRDTLDQHREVQDIMS 373

Human   151 QRVGFGDDFDEDELMAELEELEQEELNKKMTNIRLPNVPSSSLPAQPNRKPGMSSTARRSRAASS 215
            ..|......::|:|..||.||..|            :.|::..|...|..............|..
  Fly   374 NSVVENASQEDDQLEQELRELAGE------------SAPATFSPHINNNLRAEVVITDEEMIAML 426

Human   216 QRAEEEDDDIKQ 227
            |..|.||..:.|
  Fly   427 QDLEVEDGTVSQ 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CHMP4C	NP_689497.1	Intramolecular interaction with C-terminus. /evidence=ECO:0000250	1..153		29/131 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24		46/207 (22%)
		Snf7	24..190	CDD:460896	37/168 (22%)
		Intramolecular interaction with N-terminus. /evidence=ECO:0000250	154..233		16/74 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	173..233		10/55 (18%)
CG5498	NP_730525.2	Snf7	244..397	CDD:460896	36/152 (24%)