Protein Alignment DLG5 and CG5921

DIOPT Version :9

• Sequence 1: NP_004738.3
• Gene: DLG5 / 9231
• HGNCID: 2904
• Length: 1919
• Species: Homo sapiens
• Sequence 2: NP_727061.2
• Gene: CG5921 / 31538
• FlyBaseID: FBgn0029835
• Length: 886
• Species: Drosophila melanogaster
• Alignment Length: 368
• Identity: 94/368 - (25%)
• Similarity: 139/368 - (37%)
• Gaps: 99/368 - (26%)

Human  1246 MRATHGSNSLPSSARLGSSSNLQFKAERIKIPSTPRYPRSVVGSERGSVSHSECSTPPQSPLNID 1310
            |..|..|.|:.:||.|.:|::                              ::||:..|.
  Fly     2 MTMTAASASISTSASLTNSAS------------------------------TDCSSSMQG----- 31

Human  1311 TLSSCSQSQTSASTLPRIAVN-----PAS--LGERRKDRPYVEEPRHVKV---QKGSEPLGISIV 1365
              |:.|.:.:...||...|.:     |||  |...|..||:   .|.:.|   ::|| ..|.::.
  Fly    32 --STTSSASSDVMTLTTTAASSWCAIPASSRLRVLRLVRPH---QRRLLVGGPERGS-TYGFTVR 90

Human  1366 SG-EKG-GIYVSKVTVGSIAHQAGLEYGDQLLEFNGINLRSATEQQ-ARLIIGQQCDTITILAQY 1427
            .| |.| |.:||.|..|..||..||..|||:|..||..|..|..:: .:|:.||...|:.:....
  Fly    91 GGREHGTGFFVSHVEHGGEAHLKGLRIGDQILRINGFRLDDAVHKEFIQLVAGQDRVTLKVRGVG 155

Human  1428 NPHVHQLSSHSRSSSHLDPAGTHSTLQGSGTTTPEHPSVIDPLMEQDEGPSTPPAKQSSSRIAGD 1492
            ...|..|.....|.|                 ..:.|||          ..||    |.|...|:
  Fly   156 MLPVRDLPEERLSWS-----------------VVKLPSV----------SGTP----SESSFKGE 189

Human  1493 ANKKTLEPRVVFIKKSQLELGVHLCGGN--LHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDV 1555
            ....:.:..||.....:.:||:.:|.|.  ..|:||...:|.|.|: ..||.|||.||...|:|.
  Fly   190 RRGASRDISVVLHVAPRTKLGLGICKGPEWKPGIFVQFTKDRSVAR-EAGLRPGDQILSVNSIDF 253

Human  1556 RNKTVEEVYVEMLKPRDGVRLKVQYRPEEFTKAKG---LPGDS 1595
            .:....|. |.::|....:.:.|:       .|.|   .||:|
  Fly   254 SDVLFSEA-VAVMKSSSKLDMVVR-------TAAGCDLFPGES 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DLG5	NP_004738.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	98..142
		Takusan	130..212	CDD:282652
		TPR_MLP1_2	231..353	CDD:285204
		COG1340	295..587	CDD:224259
		FliJ	310..449	CDD:304890
		BAR	417..601	CDD:299863
		PDZ_signaling	620..707	CDD:238492
		DegQ	<702..771	CDD:223343
		PDZ_signaling	722..790	CDD:238492
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	927..1122
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1150..1187
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1201..1230
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1245..1264		7/17 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1271..1306		3/34 (9%)
		PDZ	1347..1429	CDD:214570	29/87 (33%)
		dbPDZ_assoc	1427..1499	CDD:293216	12/71 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1434..1493		11/58 (19%)
		PDZ	1499..1582	CDD:214570	25/84 (30%)
		SH3_DLG5	1597..1659	CDD:212794
		GuKc	1732..1908	CDD:214504
		Guanylate_kin	1740..1907	CDD:279019
CG5921	NP_727061.2	PDZ_signaling	82..152	CDD:238492	27/70 (39%)
		PDZ_signaling	197..276	CDD:238492	24/80 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900