Protein Alignment VAPA and vpr-1

DIOPT Version :9

• Sequence 1: NP_003565.4
• Gene: VAPA / 9218
• HGNCID: 12648
• Length: 294
• Species: Homo sapiens
• Sequence 2: NP_001370533.1
• Gene: vpr-1 / 172259
• WormBaseID: WBGene00018008
• Length: 245
• Species: Caenorhabditis elegans
• Alignment Length: 294
• Identity: 92/294 - (31%)
• Similarity: 142/294 - (48%)
• Gaps: 61/294 - (20%)

Human     8 MAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSGIIDPGS 72
            |::...:|.:.|..:|.|.|||:||||:::.|:|.|...||||||||||::||||||||::..|.
 Worm     1 MSEKHSLLQVTPNRELVFTGPFSDVVTSHMTLKNTSTNPVCFKVKTTAPKQYCVRPNSGLLKSGD 65

Human    73 TVTVSVMLQPFDYDPNEKSKHKFMVQTIFAP-PNTSDMEAVWKEAKPDELMDSKLRCVFEMPNEN 136
            :..::|||||.:..|::..:||||||:..|| .:..|:|:|||...|.||..|||...|.
 Worm    66 SKQITVMLQPLEGIPSDAGRHKFMVQSCVAPSEDLPDLESVWKIIDPAELTYSKLMVTFV----- 125

Human   137 DKLGITPPGNAPTVTSMSSINNTVATPASYHTKDDPRGLSVLKQEKQKNDMEPSKAVPLNASKQD 201
            ||                      ..|||   .||.:..:|..::...:.   .:|..|.:|...
 Worm   126 DK----------------------RDPAS---GDDTKTFAVRNEDSFASS---GQAQELGSSYSG 162

Human   202 GPMPKPHSVSLND---------TETRKLMEECKRLQGEMMKLSEENRHLRDEGLRLRKVAHSDKP 257
            .|   .|..::|.         .|..:|.::...|:.|:..:.::||.|:.        :|||
 Worm   163 TP---SHDGTVNSLRKSLKSTVDEKEELQKKVHGLEQEIEVMLKKNRKLQQ--------SHSD-- 214

Human   258 GSTSTASFRDNVTSPLPSLLVVIAAIFIGFFLGK 291
                 .:..|.....|...|:.:||:.||..:|:
 Worm   215 -----GALVDGAYPTLQIFLIAVAALLIGLIVGR 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VAPA	NP_003565.4	Motile_Sperm	14..118	CDD:395510	52/104 (50%)
vpr-1	NP_001370533.1	Motile_Sperm	7..112	CDD:395510	52/104 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C161470329
Domainoid	1	1.000	118	1.000	Domainoid score	I4013
eggNOG	1	0.900	-	-		E1_COG5066
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I3519
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1332028at2759
OrthoFinder	1	1.000	-	-		FOG0000705
OrthoInspector	1	1.000	-	-		mtm4945
orthoMCL	1	0.900	-	-		OOG6_101143
Panther	1	1.100	-	-	LDO	PTHR10809
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2279
SonicParanoid	1	1.000	-	-		X526
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.830