Protein Alignment VAPB and SCS22

DIOPT Version :10

• Sequence 1: NP_004729.1
• Gene: VAPB / 9217
• HGNCID: 12649
• Length: 243
• Species: Homo sapiens
• Sequence 2: NP_009461.2
• Gene: SCS22 / 852186
• SGDID: S000007228
• Length: 175
• Species: Saccharomyces cerevisiae
• Alignment Length: 229
• Identity: 62/229 - (27%)
• Similarity: 90/229 - (39%)
• Gaps: 68/229 - (29%)

Human    15 ELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGIIDAGASINVSVMLQPFDYD 79
            :|.|:.|.....|..:||.|..::.|.|||:|:||.:||||||..||.|..|:||.::.
Yeast     7 KLVFKAPLNKQSTEYIKLENDGEKRVIFKVRTSAPTKYCVRPNVAIIGAHESVNVQIVF------ 65

Human    80 PNEKSKHKFMVQSMFAPTDTSDMEAVWKEAKPEDLMDSK----LRCVFELPAENDKPHDVEINKI 140
                         :..|..|:|           |.||.|    |.....:||......|.|:
Yeast    66 -------------LGLPKSTAD-----------DEMDQKRDKFLIVTLPIPAAYQNVEDGEL--- 103

Human   141 ISTTASKTETPIVSKSLSSSLDDTEVKKVMEECKRLQGEVQRLREENKQFKEEDGLRMRKTVQSN 205
                  .::.|.:.:...   ||...||:                  |.|  ...|..||...::
Yeast   104 ------LSDWPNLEEQYK---DDIVFKKI------------------KIF--HSVLPKRKPSGNH 139

Human   206 SPISALAPT-GKEEGLSTR-LLALVVLFFIVGVI 237
            ...||.||: |..:.||:| ||.:.|:..:||.|
Yeast   140 DAESARAPSAGNGQSLSSRALLIITVIALLVGWI 173

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VAPB	NP_004729.1	Motile_Sperm	8..111	CDD:459882	29/95 (31%)
SCS22	NP_009461.2	Motile_Sperm	1..107	CDD:459882	38/138 (28%)