Protein Alignment AURKB and inaC

DIOPT Version :10

• Sequence 1: NP_001271455.1
• Gene: AURKB / 9212
• HGNCID: 11390
• Length: 345
• Species: Homo sapiens
• Sequence 2: NP_476863.1
• Gene: inaC / 36897
• FlyBaseID: FBgn0004784
• Length: 700
• Species: Drosophila melanogaster
• Alignment Length: 310
• Identity: 86/310 - (27%)
• Similarity: 150/310 - (48%)
• Gaps: 15/310 - (4%)

Human    44 RSNVQPTAAPGQKVMENSSGTPDILTRRH-FTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALK 107
            |..|:....|.:|...::...|..:::|. ....||...:.:|||.||.|.||..:.:..:.|:|
  Fly   336 RDEVRHDRRPNEKRRMDNKDMPHNMSKRDMIRAADFNFVKVIGKGSFGKVLLAERRGTDELYAVK 400

Human   108 VLFKSQ-IEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSC 171
            ||.|.. |:.:.:|..:..:..:......|.::.:::.|....|::.::||...|:|...:|:..
  Fly   401 VLRKDVIIQTDDMELPMNEKKILALSGRPPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYG 465

Human   172 TFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRR--KTM 234
            .|.|........|:|.||.:.|.:.:|:||:|.:|:||..:|.:|:.|||.|....:.|:  :|.
  Fly   466 RFKESVAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTF 530

Human   235 CGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPM 299
            |||.:|:.||::....::...|.|..|||.:|.:.|..|||.......:|.|......||....:
  Fly   531 CGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKHFSV 595

Human   300 GAQDLISKLLRHNPSERLPLA-----QVSAHP------WVRANSRRVLPP 338
            .|.|:|:..|...|:.||...     :::.||      |.:|.:..:.||
  Fly   596 EAMDIITSFLTKKPNNRLGAGRYARQEITTHPFFRNVDWDKAEACEMEPP 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AURKB	NP_001271455.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22
		Protein Kinases, catalytic domain	71..340	CDD:473864	81/283 (29%)
inaC	NP_476863.1	C1_cPKC_nPKC_rpt1	71..123	CDD:410342
		C1	137..190	CDD:412127
		C2_PKC_alpha_gamma	194..324	CDD:175992
		STKc_PKC	375..692	CDD:270722	78/271 (29%)